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Diss Factsheets
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EC number: 913-660-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 01/2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Reaction mass of glycerol and N-[3-(dimethylamino)propyl]stearamide and N-[3-(dimethylamino)propyl]docosanamide
- Molecular formula:
- C21 H50 N O C23 H54 N O C25 H58 N O C27 H62 N O
- IUPAC Name:
- Reaction mass of glycerol and N-[3-(dimethylamino)propyl]stearamide and N-[3-(dimethylamino)propyl]docosanamide
- Test material form:
- solid: flakes
Constituent 1
Test solutions
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Name of Species : Daphnia magna
No. of Daphnia group : 20 Daphnids per concentration (four replicates of single
Concentration and each containing Five Daphnids)
Temperature : 18 - 22°C
No. of Dose concentration : 5
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Details on test conditions:
- Temperature : 21.2-21.6 °C
Light conditions : 16 hours light and 8 hours dark cycle
Immobilization : In the control not more than 10 % of the Daphnia should immobilize
during the test period.
Test concentration : A limit test was performed at a dose concentration of 100 mg/l of the test
item prior to the main study. On the basis of the findings main study was
conducted by preparing five concentrations of the test item (i.e. 2, 4, 8,
10, 20 mg/l).
Carrier solvent used : Carboxymethyl Cellulose (at 30 mg/l concentration)
Water used : Ground Water
pH of water : 6.0-7.2
Dissolved oxygen : ≥ 4 mg/l content of the water - Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 48.75 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- EC50 : 48.75 mg/l of water
95 % F. limit : 40.23 - 57.17
Lowest concentration causing 100 % immobility in Daphnia : 100 mg/ l of water
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Under the conditions of this study i.e. EC50 of Daphnia with “Brassicamidopropyl Dimethylamine”
came out as:
EC50 : 48.75 mg/l of water
95 % F. limit : 40.23 - 57.17
The test item has been tested as per ‘OECD Guideline for the testing of Chemicals, Daphnia Acute
Immobilization Test Guideline No. 202 adopted on 13th April 2004’ - Executive summary:
The study was conducted to determine the ‘Immobilization test of ‘Daphnia magna’ (a benthic
zooplankton strain) with ‘Brassicamidopropyl Dimethylamine.
In the present study, a limit test was performed at 100 mg/l concentration, of the test item
‘Brassicamidopropyl Dimethylamine’ with 20 Daphnia (four replicates of five Daphnids each).
Based on the result of the limit test, the Main Test was conducted taking five different
concentrations of the test item (20, 40, 60, 80 and 100 mg/l). Similarly 20 Daphnia (four
replicates of five Daphnids each) for negative control (water) and solvent control (at 30mg/l
concentration of CMC) groups were used (the volume of solvent, used in the test concentrations
and control was kept same).
On the basis of these concentrations, the EC50 was estimated, which came out as:
EC50 : 48.75mg/l of water
95 % F. limit : 40.23 - 57.17
Lowest concentration causing 100 % immobility in Daphnia : 100 mg/ l of water
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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