Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 238-015-1 | CAS number: 14171-00-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 96 hours
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Justification for type of information:
- Data refers to sodium salt.
Triethanolamine is not classified as hazarodus in the environment and the sodium salt is considered a suitable surrogate for read-across
No further animal testing can be justified. - Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes
- Analytical monitoring:
- not required
- Vehicle:
- no
- Details on test solutions:
- Dilutions in water
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- The fish were fed daily to repletion with commercial trout pellets but food was not given during the 24 hour period immediately prior to exposure or during the exposure period itself.
No medication was given during the acclimatisation period and mortalities were recorded as < 1 % in the 7 days prior to the test.
The size of the fish used in the test was determined by measuring the control fish at the end of the exposure period.
The mean standard length was found to be 4.7 cm (SD = 0.4 cm) and the mea.'1 weight determined as 1.3 g (SD = 0.4 g). - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- Chlorine levels remained below the limit of detection throughout the acclimatisation and exposure periods
The mean hardness level, calculated from daily measurements during the same period, was determined as 154 mgCaC03/1. - Test temperature:
- 14 C (+/- 1C)
- pH:
- 7.7 - 7.7 during the study
- Dissolved oxygen:
- 9.85 - 9.97 mg/O2 / litre
The mean values lowered from starting levels of 9.97 to the final figure at 96 hours of 9.85. - Nominal and measured concentrations:
- Nominal test concentrations: 0.56, 1.0, 1.8, 3.2, 5.6, 10 mg actives/litre
- Details on test conditions:
- Treatment and control groups were maintained at 14 ± I°C throughout the exposure period.
Supplementary aeration was provided via narrow bore glass tubes.
A photoperiod of 16 h light: 8 h dark was established and daily records of temperature, pH and dissolved oxygen were maintained for each control and test vessel
The fish were not fed during the 96 hour exposure period. - Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 3.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 3.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC100
- Effect conc.:
- ca. 5.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- ca. 5.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 4.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Details on results:
- There were no mortalities at 3.2 mg/l actives or lower, but the next highest test concentration, 5.6 mg/l, resulted in 100% mortality.
Loss of equilibrium was observed in fish before death. None of the surviving fish showed adverse effects. - Validity criteria fulfilled:
- yes
- Conclusions:
- Appears toxic to aquatic orgnaisms. Stable in water.
- Executive summary:
Very narrow concentration range showing no effect or 100% mortality.
Even without full analysis, the known stability of the substance in water and the ease to dilute an aqueous solution led to the conclusion that analysis was not required. The study is considered valid without analysis and repeating the study on vertebrates is not appropriate.
It is predicted that the triethanolamine salt will have a lower toxicity in view of the low biological effect of triethanolamine and the molecular weight difference between triethanolamine and sodium; however, due to uncetainty factors in read-across, it is assumed that the toxicity of the triethanolamine salt will be equivalent to that of the sodium salt.
Reference
Description of key information
Considered toxic to fish
Data refers to sodium salt.
Triethanolamine is not classified as hazarodus in the environment and the sodium salt is considered a suitable surrogate for read-across
No further animal testing can be justified.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 4.2 mg/L
Additional information
Key study showed 100% mortality at 3.2 mg/l and no observed effect at 5.6 mg/l
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.