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EC number: 273-159-9 | CAS number: 68951-62-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From September 15, 2017 to December 18, 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Study results suspected to be influenced by trapped gases/impurities
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- static method
- Key result
- Test no.:
- #1
- Temp.:
- ca. 20 °C
- Vapour pressure:
- ca. 3.7 Pa
- Remarks on result:
- other: Mean of run 3 and 4
- Conclusions:
- Under study conditions, the vapour pressure of the test substance was determined to be 3.7 Pa at 20°C.
- Executive summary:
A study was conducted to determine the vapour pressure of the test substance, C16 -18 AMP, using the static method, according to EU Method A.4, static method, in compliance with GLP. In the study, the results from runs 1 and 2 indicated a phase change at about 40°C. Some variability was noted in the values obtained at 20°C for runs 1 and 2. Two additional determinations were made at 20°C with increased degassing periods and which gave similar results. The mean of the last two determinations, 3.7 Pa has been reported as a result by study author. Under study conditions, the vapour pressure of the test substance was determined to be 3.7 Pa at 20°C (Chilworth, 2017). The study results are suspected to be influenced by trapped gas/impurities.
Reference
Full test results
Temp / °C |
Temp / K |
P / mbar |
P / Pa |
|
Run 1 |
||||
20 |
293.15 |
0.51 |
51 |
|
20.0 |
293.15 |
0.2824 |
28.24 |
|
30.2 |
303.35 |
1.4 |
140 |
|
40.0 |
313.15 |
3.6 |
360 |
|
50.0 |
323.15 |
3.2 |
320 |
|
60.0 |
333.15 |
3.4 |
340 |
|
Run 2 |
||||
20 |
293.15 |
0.30 |
30 |
|
20.0 |
293.15 |
0.1683 |
16.83 |
|
30.0 |
303.15 |
0.7466 |
74.66 |
|
40.0 |
313.15 |
2.1 |
210 |
|
50.0 |
323.15 |
1.9 |
190 |
|
60.6 |
333.75 |
1.8 |
180 |
|
Run 3 |
||||
20 |
293.15 |
0.0319 |
3.19 |
|
Run 4 |
||||
20 |
293.15 |
0.0413 |
4.13 |
Comment
Run1 : Sample ground into a powder. 10.4 g test substance degassed: 16 h, Starting vacuum pressure: 0.0010 mbar. Sample melted at approximately 45°C and became a milky colour suspension.
Run2 : Sample ground into a powder. 11 g test substance degassed: 19 h, Starting vacuum pressure: 0.0011 mbar. Sample melts at approximately 45°C and became a milky colour suspension.
Run3 : Sample ground into a powder. 9.4 g test substance degassed: 26 h, Starting vacuum pressure: 0.0008 mbar.
Run4 : Sample ground into a powder. 9.4 g test substance degassed: 96 h, Starting vacuum pressure: 0.0007 mbar.
The results from runs 1 and 2 indicated a phase change at about 40°C. Some variability was noted in the values obtained at 20°C for runs 1 and 2. Two additional determinations were made at 20°C. Both these runs had increased degassing periods and gave similar results. It is the mean of the last two determinations that has been reported as the result.
Description of key information
The vapour pressure of the test substance was determined experimentally using the static method, according to EU Method A.4, (Chilworth, 2017) as well as using the QSAR models, EPI Suite and TEST (US EPA, 2018).
Key value for chemical safety assessment
- Vapour pressure:
- 3.7 Pa
- at the temperature of:
- 20 °C
Additional information
- Experimental VP = 3.7 Pa at 20 °C (static method); study results are suspected to be influenced by trapped gas/impurities.
- Weighted average QSAR based VP = 0.00179 Pa at 25°C (EPI Suite v.4.11) and 0.000208 Pa at 25°C (T.E.S.T. v4.2.1). The estimates for the major constituents are considered to be reliable with restrictions, as they do not completely fall within of the applicability domain.
- Experimental VP of structurally similar substance, Oleamide MIPA: 2.42E-6 Pa at 25°C (using gas saturation method).
Overall, based on the above information, the test substance can be considered to have low volatility. However, the higher VP value of 3.7 Pa has been considered further for hazard/risk assessment as a conservative approach.
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