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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
4 - 11 June 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Other quality assurance:
other: ISO 13320-1 test standard.
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
mass based distribution
Mass median aerodynamic diameter:
465 µm
Geometric standard deviation:
0.003
Key result
Percentile:
D10
Mean:
120 µm
St. dev.:
0.096
Key result
Percentile:
D50
Mean:
197 µm
St. dev.:
0.551
Key result
Percentile:
D90
Mean:
312 µm
St. dev.:
0.718

Test Results

 

 

RUN 1

RUN 2

RUN 3

RUN 4

RUN 5

Average

**

Volume weighted mean

209

208

208

208

208

208

Median

198

197

197

197

196

197

Mode

202

201

201

202

201

202

MMAD *

467

465

465

466

464

464

d10 (10 % of material is <)

121

120

120

121

120

120

d50 (50 % of material is <)

198

197

197

197

196

197

d90 (90 % of material is <)

314

312

311

313

308

312

All results are in μm

*Mass median aerodynamic diameter

**Average result is calculated from the entirety of data captured in each run and is not a simple arithmetic mean.

0.0    % by volume of sample was seen to be < 10.00 μm.

Standard Deviation results

Run No.

1

2

3

4

5

STDVP

%

STDVP

d10 (10 % of material is <)

121

120

120

121

120

0.0956

0.0794

d50 (50 % of material is <)

198

197

197

197

196

0.551

0.280

d90 (90 % of material is <)

314

312

311

313

308

2.24

0.718

GSD

1.430

1.427

1.426

1.428

1.421

0.003

0.2

MMAD

467

465

465

466

464

1.164

0.3

GSD = Geometric standard deviation of the lognormal particle size distribution (calculated from d50/d15.78)

STDVP = standard deviation of the population

% STDVP = percentage standard deviation of the population

Coefficient of variation for d50 is less than 3%; d10 and d90 are less than 5%. Thus repeatability of the characteristic particles in the size distribution are within the acceptable limits as per the ISO 13320-1 test standard.

Conclusions:
The particle size of cadmium selenide was determined with laser diffraction particle size analysis. The study concluded as follows:

Particle Size Analysis using small volume (wet) module Average (μm)
Volume weighted mean 208
Median (d.50) 197
Mode 202
MMAD (Mass Median Aerodynamic Diameter) 465
10 % of material is < 120
50 % of material is < 197
90 % of material is < 312
by volume of sample was seen to be < 10.00 μm 0.00 %
Executive summary:

A study was conducted on Cadmium selenide in accordance with OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius).

Preliminary investigations using standard visual observations and observations under the microscope of 100 and 400 x magnification revealed the following on the test substance:

Visual observations

Gritty, coarse to medium free flowing black powder.

Observation at 100 x magnification

The particles appeared to be irregular shaped crystals. The smallest individual particle

size was approximately 128 μm and the largest individual size was approximately 480 μm.

Observation at 400 x magnification

The sample was observed to be made up of single crystalline particles

Laser diffraction particle size analysis conducted in accordance with ISO 13320:2009 “Particle Size Analysis– Laser Diffraction Methods”, 2009 and CIPAC MT 187 “Particle Size Analysis by Laser Diffraction”, Handbook K, 2007. Revealed the following:

 

Particle Size Analysis using small volume (wet) module (SVM).

Average (μm)

Volume weighted mean

208

Median (d.50)

197

Mode

202

MMAD (Mass Median Aerodynamic Diameter)

465

10 % of material is <

120

50 % of material is <

197

90 % of material is <

312

by volume of sample was seen to be < 10.00 μm

0.00 %

 

Description of key information

The particle size of cadmium selenide was determined with laser diffraction particle size analysis. The study concluded as follows:

Particle Size Analysis using small volume (wet) module       Average (μm)

Volume weighted mean                                                        208

Median (d.50)                                                                     197

Mode                                                                                  202

MMAD (Mass Median Aerodynamic Diameter)                   465

10 % of material is <                                                            120

50 % of material is <                                                            197

90 % of material is <                                                            312

by volume of sample was seen to be < 10.00 μm                  0.00 %

Additional information

A study was conducted on Cadmium selenide in accordance with OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius).

Preliminary investigations using standard visual observations and observations under the microscope of 100 and 400 x magnification revealed the following on the test substance:

Visual observations

Gritty, coarse to medium free flowing black powder.

Observation at 100 x magnification

The particles appeared to be irregular shaped crystals. The smallest individual particle

size was approximately 128 μm and the largest individual size was approximately 480 μm.

Observation at 400 x magnification

The sample was observed to be made up of single crystalline particles

Laser diffraction particle size analysis conducted in accordance with ISO 13320:2009 “Particle Size Analysis– Laser Diffraction Methods”, 2009 and CIPAC MT 187 “Particle Size Analysis by Laser Diffraction”, Handbook K, 2007. Revealed the following:

 

Particle Size Analysis using small volume (wet) module (SVM).

Average (μm)

Volume weighted mean

208

Median (d.50)

197

Mode

202

MMAD (Mass Median Aerodynamic Diameter)

465

10 % of material is <

120

50 % of material is <

197

90 % of material is <

312

by volume of sample was seen to be < 10.00 μm

0.00 %