Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 946-958-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The registered substance is a UVCB. A biodegradation study on the substance itself has been used to assess the biodegradation properties of the substance for the purpose of classification and labelling. The data indicates that the substance and its underlying constituents are readily biodegradable. In order to assign a biodegradation rate to the two assessment entities being used for the environmental exposure and risk assessment, available experimental data on Hydroxycitronellal and Methyl Anthranilate (methyl 2-aminobenzoate) has been used. Both of these individual substances are readily biodegradable. Therefore the key value of "readily biodegradable" has been assigned to all assessment entities. For the PBT assessment, data on the whole substance and the assessment entities has been considered.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
One biodegradation study is available for the registered substance, Aurantiol Pure. The ready biodegradability has been investigated using a standard ready screening method, the OECD 301F Manometric Respirometry Test (Key study, Rudio 1999). The percentage of biodegradation achieved after 28 days was 70%. Biodegradation starts on day 3 and reaches 63% at the end of the 10 day window (days 3 to 13). Thus Aurantiol Pure was regarded as readily biodegradable according to this test.
Aurantiol Pure is a UVCB. It is recognised that standard biodegradation tests are not ideally suited to mixtures because they measure ultimate biodegradation as a function of either the CO2 evolved or O2 consumed and as such do not provide information on the biodegradability of individual constituents. However, the registered substance is a mixture of reaction products which are unstable in solution, being on purpose, precursors for Methyl Anthranilate and Hydroxycitronellal. Thus for the purposes of the PBT assessment and in order to assign a biodegradation rate to the two assessment entities for environmental risk assessment, available information on these two individual substances has been used. The ready biodegradability of Methyl Anthranilate (Rudio 1996) and Hydroxycitronellal (King 1994) were determined in separate standard biodegradation screening tests (OECD301F and sealed CO2 test respectively). The levels of biodegradation achieved after 28 days were respectively 85% and 94%. The 10 day window was met in both cases. Thus Methyl Anthranilate and Hydroxycitronellal are regarded as readily biodegradable according to these tests.
In the neat state, the registered substance contains some Methyl Anthranilate and Hydroxycitronellal as remaining starting materials (approximate total weight 29%). The fact that the degradation levels observed in the test performed on Aurantiol Pure were significantly higher than 29%, indicate that the condensation products in Aurantiol Pure are either rapidly hydrolysed to Methyl Anthranilate and Hydroxycitronellal and/or rapidly biodegraded themselves. Thus Aurantiol Pure and its underlying constituents are regarding as rapidly biodegradable for the purposes of classification and labelling and PBT assessment.
An inhibition control was included in the 301F ready biodegradability test performed on Hydroxycitronellal (Rudio, 1996). At the concentration used in the test (100mg/l), Hydroxycitronellal was not inhibitory to the microorganisms. Methyl anthranilate was shown to be readily biodegradable in a test performed at 10mg/L (King, 1994). These concentrations can be considered as NOECs for the toxicity to STP microorganisms for the two respective assessment entities (see endpoint on toxicity to microorganisms for further details).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.