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Diss Factsheets
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EC number: 211-734-8 | CAS number: 692-86-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29 Jul - 01 Sep 1993
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 993
- Report date:
- 1993
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- yes
- Remarks:
- activated sludge was used instead of effluent
- GLP compliance:
- yes
Test material
- Reference substance name:
- Isopropyl laurate
- EC Number:
- 233-560-1
- EC Name:
- Isopropyl laurate
- Cas Number:
- 10233-13-3
- Molecular formula:
- C15H30O2
- IUPAC Name:
- isopropyl laurate
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Secondary activated sludge obtained from the Waste water treatment plant Nieuwgraaf in Duiven, The Netherlands on 29th July 1993; treating predominantly domestic waste water
- Pretreatment: Sludge was preconditioned to reduce the endogenous respiration rates; aerated for one week
- Concentration of sludge: 200 mg DW/L
- Test concentration of sludge: 2 mg DW/L - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 7.1 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: nutrient medium containing 8.5 mg/L KH2PO4, 21.75 mg/L K2HPO4, 33.3 mg/L Na2HPO4, 22.5 mg/L MgSO4, 27.5 mg/L CaCl2 and 0.25 mg/L FeCl3
- Test temperature: 21 ± 1 °C
- pH: 7.1 at begin, 6.8 and 6.6 at test end
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus: BOD bottles, 250 or 300 mL volume
- Number of culture flasks/concentration: 10 bottles containing only inoculum, 10 bottles containing inoculum + test substance, 10 bottles containing sodium acetate and inoculum
- Measuring equipment: oxygen electrode (WTW Trioxmatic EO 200) and oxygen meter (WTW OXI 530);
SAMPLING
- Sampling frequency: Days 0, 7, 14, 21 and 28
- Sampling method: Removal of two bottles per measuring date
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, 10 replicates
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 67
- Sampling time:
- 28 d
- Details on results:
- The substance is readily biodegradable (pass level > 60% within 14 days)
BOD5 / COD results
- Results with reference substance:
- The reference substance (sodium acetate; 6.7 mg/L) was biodegraded to 77% after 28 days.
Any other information on results incl. tables
Table 1: Biodegradation in %:
|
Biological degradation |
||||
Test substance |
% BOD 0 days |
% BOD 7 days |
% BOD 14 days |
% BOD 21 days |
% BOD 28 days |
CAS 10233-13-3 |
0 |
48 |
62 |
68 |
67 |
Na-acetate-3-hydrate |
0 |
69 |
77 |
- |
- |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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