Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 813-616-7 | CAS number: 76883-37-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
In case of skin contact: immediately flush with plenty of soap and water for at least 15 minutes. Remove contaminated clothes and shoes. Seek medical attention in event of irritation.
In case of eye contact: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. If pain persists or recurs seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. Get medical aid immediately.
If swallowed: Rinse mouth with water. Immediately give a glass of water. First aid is not generally required. If in doubt, contact a Poisons Information Center or a doctor.
Most important symptoms and effects, both acute and delayed.
The material may still be damaging to the health of the individual, following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, unintentional ingestion is not thought to be cause for concern.
Direct contact with the eye may cause transient discomfort characterized by tearing or conjunctival redness (as with windburn). Slight abrasive damage may also result. The material may produce foreign body irritation in certain individuals. Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.
CHRONIC HEALTH EFFECTS
Skin contact with the material is more likely to cause a sensitization reaction in some persons. Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis; caused by particles less than 0,5 micron penetrating and remaining in the lung. Prime symptom is breathlessness; lung shadows show on X-ray.
Fire-fighting measures
Accidental release measures
Use personal protective equipment: wear self - contained breathing apparatus, rubber boots and heavy rubber gloves. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
For non-emergency personnel
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
For emergency responders
Wear self - contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Environmental precautions - do not let product enter drains.
Methods and material for containment and cleaning up
MINOR SPILLS: Remove all ignition sources. Clean up all spills immediately. Avoid contact with skin and eyes. Control personal contact by using protective equipment. Use dry clean up procedures and avoid generating dust. Place in a suitable, labelled container for waste disposal.
MAJOR SPILLS: Advise personnel in area. Alert Emergency Responders and tell them location and nature of hazard. Control personal contact by wearing protective clothing. Prevent, by any means available, spillage from entering drains or water courses. Recover product wherever possible.
Use dry clean up procedures and avoid generating dust. Collect residues and place in sealed plastic bags or other containers for disposal. Wash area down with large amounts of water. If contamination of drains or waterways occurs, advise emergency services.
Handling and storage
Keep containers securely sealed when not in use. Avoid physical damage to containers. Always wash hands with soap and water after handling. Work clothes should be laundered separately. Launder contaminated clothing before re-use. Use good occupational work practice. Observe manufacturer's storing and handling recommendations.
Store in a cool, dry place. Store in well-ventilated area away from incompatible substances. Keep container tightly closed when not in use. Recommended storage: lined metal can, lined metal pail/drum, plastic pail, polyliner drum. Store in original containers. Keep containers securely sealed. Check all containers are clearly labelled. Protect containers against physical damage and check regularly for leaks. Keep away from sources of ignition.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- not dangerous goods
Shippingopen allclose all
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- not dangerous goods
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- not dangerous goods
Shipping information
- Proper shipping name and description:
- not dangerous goods
- Chemical name:
- Quinuclidin-3-one oxime hydrochloride
- Labels:
- not dangerous goods
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- not dangerous goods
Shipping information
- Proper shipping name and description:
- not dangerous goods
- Chemical name:
- Quinuclidin-3-one oxime hydrochloride
- Labels:
- not dangerous goods
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Individual protection measures, such as personal protective equipment
Eye / face protection - For laboratory, larger scale or bulk handling or where regular exposure in an occupational setting occurs: chemical goggles.
Full face shield may be required for supplementary but never for primary protection of eyes.
Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. This should include a review of lens absorption and adsorption for the class of chemicals in use and an account of injury experience. DO NOT wear contact lenses.
Skin and body protection - Choose body protection according to the amount and concentration of the dangerous substance at the work place.
Hand protection - The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 and US F739. Suitability and durability of glove type is dependent on usage. Important factors in the selection of gloves include such as: frequency and duration of contact, chemical resistance of glove material, glove thickness and dexterity.
When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time greater than 240 minutes according to EN 374) is recommended.
When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374) is recommended. Contaminated gloves should be replaced.
Other - barrier cream, skin cleansing cream, eye wash unit.
Respiratory protection - where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respirators may be necessary when engineering and administrative controls do not adequately prevent exposures. The decision to use respiratory protection should be based on professional judgment that takes into account toxicity information, exposure measurement data, and frequency and likelihood of the worker's exposure - ensure users are not subject to high thermal loads which may result in heat stress or distress due to personal protective equipment (powered, positive flow, full face apparatus may be an option). Certified respirators will be useful for protecting workers from inhalation of particulates when properly selected and fit tested as part of a complete respiratory protection program. Use approved positive flow mask if significant quantities of dust becomes airborne.
Thermal hazards - none.
Hygiene measures - handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Wash contaminated clothing before reuse. Discard contaminated shoes. When handling, DO NOT eats, drink or smoke.
Environmental exposure controls. Contact a licensed professional waste disposal service to dispose of this material. Do not let product enter drains.
Stability and reactivity
Chemical stability - Stable under recommended storage conditions.
Possibility of hazardous reactions - Avoid contamination with oxidizing agents i.e. nitrates, oxidizing acids, chlorine bleaches, pool chlorine etc.
Conditions to avoid - sources of ignition, moisture, light.
Incompatible materials - strong oxidizing agents.
Hazardous decomposition products - Hazardous decomposition products formed under fire conditions - carbon monoxide CO, carbon dioxide CO2, nitrogen oxides NOx, chlorine Cl2, hydrogen chloride HCl gas and other pyrolysis products typical of burning organic material.
Disposal considerations
Consult Waste Management Authority for disposal if no suitable treatment or disposal facility can be identified. Dispose in Incineration in a licensed apparatus (after admixture with suitable combustible material). Decontaminate empty containers. Observe all label safeguards until containers are cleaned and destroyed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.