Registration Dossier
Registration Dossier
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EC number: 217-442-7 | CAS number: 1852-16-0
Endpoint summary
Administrative data
Description of key information
The biodegradation of the test material was assessed over 28 days according to OECD Test Guideline 301C using a modified MITI test. The average degradation by BOD was 76 % and is therefore considered readily biodegradable.
The biodegradation of the read-across material, acrylamide, was assessed over 28 days according to OECD test guideline 301 D using a closed bottle test. The test material was found to degrade approximately 100 % and is also considered readily biodegradable.
Additional information
The biodegradation of the test material was assessed over 28 days according to OECD Test Guideline 301C using a modified MITI test. Non-adapted activated sludge was used as the inoculum and the study was performed under aerobic conditions. In the procured test sample there was around 7 % impurity and this insoluble matter remained in HPLC analysis, however, structural estimation could not be done. The test article did not remain. The degradation after 7 days and 14 days of the reference substance, aniline, that is derived by BOD is respectively 69 % and 76 %, thereby confirming that the conditions of the test are valid.
The average degradation by BOD of the test material was 76 % and is therefore considered readily biodegradable.
The biodegradation of the read-across material, acrylamide, was assessed over 28 days according to OECD test guideline 301D using a closed bottle test. Non-adapted activated sludge was used as the inoculum and the study was performed under aerobic conditions. Degradation was followed by oxygen analyses with the YSI Dissolved Oxygen Analyzer 54A over a 28-day period. Degradability was based on a comparison of readings of actual oxygen demand to the theoretically expected oxygen demand. A parallel control with inoculum, but without test material, was run as a blank correction factor. The procedure was validated by means of a reference substance (aniline, 2 mg/L) of known biodegradability.
The reference material, aniline, degraded approximately 98 % in concurrent testing and was considered readily biodegradable because it achieved a degradation of greater than 70 %.
The test material was found to degrade approximately 100 % and is also considered readily biodegradable.
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