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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

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Endpoint:
short-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
no data
Test type:
other: (Q)SAR
Water media type:
freshwater
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
391.4 mg/L
Sublethal observations / clinical signs:

ECOSAR Program (v1.11) Results:

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Aliphatic Amines: Maximum LogKow: 6.0 (Fish LC50 96h)
Conclusions:
Estimated LC50 (96 h) : 391 mg/L
Intermediate substance is not estimated to be toxic to fish (acute toxicity).
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1997-07-15 1997-07-18
Reliability:
2 (reliable with restrictions)
Qualifier:
according to guideline
Guideline:
other: NFT 90.303
Deviations:
yes
Remarks:
5 fishes instead of 7
GLP compliance:
no
Specific details on test material used for the study:
Bicrist OHquinu mélange reliquats divers 1ère partie
Analytical monitoring:
no
Vehicle:
not specified
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h
Hardness:
256.3 mg CaCO3/L
pH:
7.7
Dissolved oxygen:
98%
Conductivity:
584 µS/cm
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Results with reference substance (positive control):
potassium dichromate CL50-24h=230.2 mg/L
Conclusions:
CL50-96h >100 mg/L
Intermediate substance is not estimated to be toxic to fish (acute toxicity).

Description of key information

ECOSAR 1.11: Fish: LC50 (96h): 391 mg/L

Experimental data : Fish: LC50 (96h) > 100 mg/L

Key value for chemical safety assessment

Additional information

Intermediate substance is not estimated to be toxic to fish (acute toxicity).