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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 200-926-7 | CAS number: 76-02-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Cross-reference
- Reason / purpose for cross-reference:
- other: Reference to same publication
Reference
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Reason / purpose for cross-reference:
- other: reference to the same publication
- Principles of method if other than guideline:
- No data
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Vehicle:
- not specified
- Details on test solutions:
- Test solutions were prepared in well water having a total alkalinity of 138 mg/L. A photoperiod of 16h light/8h dark was maintained.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- The daphnia were less than 24 h old.
- Test type:
- static
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 192 mg/L
- Test temperature:
- 20°C ± 1°C
- pH:
- 8.2
- Nominal and measured concentrations:
- No data
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 12
Daphnia tests were performed in 205-mL beakers containing 200 mL of test solution.
The number of survivors in each test concentrations was monitored daily (swimming ability was the criterion for survival).
The 48h-EC50 (median effective concentration, i.e., concentration which immobilized 50% of the exposed animals) was calculated by means of the method of Litchfield and Wilcoxon. - Reference substance (positive control):
- not specified
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 2 000 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- No data
- Reported statistics and error estimates:
- No data
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 48-hour EC50 was 2000 mg/L. Trichloroacetic acid is not harmful to daphnia.
- Executive summary:
The objective of the study was to determine the acute toxicity of Trichloroacetic acid (TCA) to Daphnia magna.
The 48 -hour EC50 was determined to be 2000 mg/L.
In these test conditions, TCA is not harmful to daphnia.
Data source
Reference
- Reference Type:
- publication
- Title:
- Degradation of Diazinon by Sodium Hypochlorite. Chemistry and Aquatic Toxicity
- Author:
- William H. Dennis, Jr., Eugene P. Meier, William F. Randall, Alan B. Rosencrance and David H. Rosenblatt
- Year:
- 1 979
- Bibliographic source:
- Environmental Science & Technology, Volume 13, Number 5, May 1979, 594-598
Materials and methods
- Principles of method if other than guideline:
- No data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Trichloroacetic acid
- EC Number:
- 200-927-2
- EC Name:
- Trichloroacetic acid
- Cas Number:
- 76-03-9
- Molecular formula:
- C2HCl3O2
- IUPAC Name:
- trichloroacetic acid
- Test material form:
- solid
- Details on test material:
- No data available
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- Test solutions were prepared in well water having a total alkalinity of 138 mg/L. A photoperiod of 16h light/8h dark was maintained.
Test organisms
- Test organisms (species):
- Pimephales promelas
- Details on test organisms:
- The fish were less than 1 year old.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 192 mg/L
- Test temperature:
- 20°C ± 1°C
- pH:
- 8.2
- Nominal and measured concentrations:
- No data
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 2
Fish tests were conducted in 19-L jars containing 14 L of test solution.
The number of survivors in each test concentrations was monitored daily.
The 96h-LC50 (median lethal concentration, i.e., concentration lethal to 50% of the exposed animals) was calculated by means of the method of Litchfield and Wilcoxon. - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 2 000 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- No data
- Reported statistics and error estimates:
- No data
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Under the test conditions, the 96-hour LC50 was 2000 mg/L. Trichloroacetic acid is not harmful to fish.
- Executive summary:
The objective of the study was to determine the acute toxicity of Trichloroacetic acid (TCA) to Pimephales promelas.
The 96 -hour LC50 was determined to be 2000 mg/L.
In these test conditions, TCA is not harmful to fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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