Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 246-426-2 | CAS number: 24717-85-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22 September to 15 November 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Federal Office for the Environment (FOEN)
- Type of method:
- slow-stirring method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 5.99
- Temp.:
- 25 °C
- Remarks on result:
- other: pH is not reported
- Conclusions:
- A log Pow of 5.99 ± 0.10 at 25°C was determined for the test substance according to OECD 123.
Reference
Results
Thermostated glass flasks containing the aqueous phase and n-octanol were slowly stirred, after dosing the test item dissolved in octanol, until equilibrium distribution of the test item between the two phases was achieved. The temperature was kept constant at 25 °C ± 1 °C. The concentration of the test item in the phases was measured by HPLC/UV. The partition coefficient (n-octanol/water) log Pow was calculated. The equilibrium distribution was defined to be achieved, when four sampling intervals separated by at least 5 hours yielded similar log Pow values, expressed by a plateau with zero slope. The testing was performed in triplicate.
The results of the individual measurements of the slow-stirring test and the calculation of the log Pow values are given in the table below.
Slow-Stirring Test - Results obtained for log Pow.The tabulated values of the samples represent rounded results obtained by calculation using the exact data.
Stirring Time [hours] |
Measured Concentration in n- Octanol [μg/L] |
Measured Concentration in Water [μg/L] |
Log Pow |
|||||||
|
Test 1 |
Test 2 |
Test 3 |
Test 1 |
Test 2 |
Test 3 |
Test 1 |
Test 2 |
Test 3 |
mean |
168 |
20961179 |
20525802 |
21014367 |
11.1 |
16.3 |
17.8 |
6.28 |
6.1 |
6.07 |
6.15 |
173 |
22206444 |
22625919 |
20681529 |
18.8 |
25.2 |
32.8 |
6.07 |
5.95 |
5.8 |
5.94 |
192 |
19810775 |
20643146 |
22907214 |
18.4 |
24.2 |
31.5 |
6.03 |
5.93 |
5.86 |
5.94 |
197 |
17405237 |
21014916 |
21071394 |
18.3 |
24.7 |
32 |
5.98 |
5.93 |
5.82 |
5.91 |
Means: |
6.09 |
5.98 |
5.89 |
5.99 |
||||||
Overall mean |
5.99 ± 0.10 (1.7% RSD) |
Description of key information
Log Pow: 5.99 ± 0.10 at 25°C (OECD 123, Slow-Stirring Method)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 5.99
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.