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Diss Factsheets
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EC number: 620-459-6 | CAS number: 130841-23-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene
- EC Number:
- 620-459-6
- Cas Number:
- 130841-23-5
- Molecular formula:
- C9H3Cl2F6NO3
- IUPAC Name:
- 1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene
- Details on test material:
- - Name of test material: CA 946 A
- Batch No.: P.906005
- Purity: 96,9%
- Received: 1993-12-15
- Storage: room temperatur
- Stability: 07/96
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Samples (about 150 ml in duplicate) of each test concentration were drawn from the approximate center of the test vessels. They were takeno immediately before the exposure and after 96 hours exposure and kept at -18 to -22 °C until analysis (see Attachment Table 4)
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- - Vehicle: 70,0 mg dimethylformamide (DFM) and 2,9 mg polyoxy-ethylene-sorbitan-monooleate (TWEEN80)/1
- Stock solution: 54,3 mg test substance were added to a mixture of 3,2 g of dimethylformamide (DFM) and 0,1 mg polyoxy-ethylene-sorbitan-monooleate (TWEEN80)/1
Test organisms
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: Rainbow trout
- Source: P. Hohler / CH-4314 Zeiningen
- Length at study initiation (mean): 51 mm (45-57 mm) based on 7 fishes
- Weight at study initiation (mean): 1,07 g (0,61-1,42 g) based on 7 fishes
- Loading: 0,50 g/l
- Feeding: none
- Adaption: 24 hours / no food 24 hours prior to exposure
- Acclimatization: 26 days
- Treatment: None
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 190 mg CaCo3/1
- Test temperature:
- 14 +/- 1 °C
- Nominal and measured concentrations:
- Nominal: 0,052 / 0,114 / 0,25 / 0,55 and 1,2 mg test substance/l
Actual end: < 0,004 / < 0,016 / < 0,019 / 0,027 and 0,58 mg test substance/l - Details on test conditions:
- TEST SYSTEM
- Vessels: Glass aquaria of 20 liters filled with 15 liters (36/22/25 cm)
- Aeration: Gentle aeration during exposure
- Water: Dechlorinated tap water (carbon filter)
- Lightning: Fluorescent light, 16 hours daily
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.13 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% CL
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.