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Diss Factsheets
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EC number: 203-427-2 | CAS number: 106-72-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term aquatic toxicity data are available for each of the three freshwater trophic levels (fish, daphnia and algae).
An experimental study is available for daphnia which gave a 48h EC50 of 2.4mg/L.
In the absence of experimental data, the use of QSAR predicted values has been used to assess toxicity to fish and algae. Two well-established software tools have been used, ECOSAR v1.11 and OECD QSAR Toolbox v3.4.0.17. The predicted 96 hour Fish LC50 values range from 2.3 -7.6mg/L and the algae EC50 values from 4.3 -11.9 mg/L.The prediction result using the ECOSAR Aldehydes (mono) SAR has been chosen as the key value for both fish and algae since it is the most conservative value. Furthermore, the applicability of the Aldehydes (mono) SAR class to the prediction of aquatic toxicity for the registration substance is supported by a comparison of predicted and measured values for the daphnia endpoint (2.3 and 2.4 mg/L respectively – see QPRF documents for prediction of fish 96h LC50 and algae EC50 using ECOSAR v1.11).
The registration substance is a mono-constituent substance. All QSAR results reported are for the main constituent, 2,6-dimethylhept-5 –enal. Impurities present in the registration substance were also considered. Details are provided in the supporting QPRF documents for the ECOSAR v.11 predictions and IUCLID endpoint records. In summary, ECOSAR v1.11 assigns all impurities to the neutral organic ECOSAR class and predicts lower toxicity than for the main constituent. For example, the predicted Green Algae 96-hr EC50 values for the impurities range from 11.9 to 39.7 mg/L (Neutral Organic SAR). In contrast, the main constituent has a predicted EC50 of 4.3 mg/L (Aldehyde Mono SAR). Similarly for fish, the predicted 96-hr LC50 values for the impurities range from of 18.5 to 91.3 mg/L (Neutral Organic SAR) while the predicted value for the main constituent is 2.3mg/L (Aldehyde Mono SAR). Therefore, an assessment of the aquatic toxicity of the registration substance based only on the major constituent is considered justifiable and worst-case.
Toxicity to microorganisms was assessed as part of a standardised ready biodegradation test. The substance did not inhibit degradation of the positive control at a test concentration of 100mg/L. Thus this concentration can be considered the NOEC for toxicity to STP microorganisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.