Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 944-209-3
CAS number: -
The n-octanol/water partition coefficient log Kow was investigated in a
study conducted according to OECD Guideline 122 'Partition coefficient
n-octanol/water, pH-metric method for ionisable substances' (draft).
Although the method is only valid for pure substances it was applied to Amides,
C8-18 even numbered, N-[3-(dimethylamino)propyl] which represents
a complex mixture. Thus, log Kow can only be determined as an average or
as a range of individual data. In order to validate the log Kow
estimation, the method was additionally applied to two of the main
consituents which were available as pure substances. The log Kow of
various amido-amines of different chain length were estimated to:
-Amides, C8-18 even numbered, N-[3-(dimethylamino)propyl]:
-N-(3-(dimethylamino)propyl)dodecanoic acid amide: 3.3
-N-(3-(dimethylamino)propyl)octanoic/decanoic acid amide: 3.3
According to guideline, the method can not be applied to surface-active
substances: Amido-amines may provide a surface active behaviour in
-these influences might be the reason for the disturbed titration curves
recorded under addition of n-octanol
-the measured pKa data did not correlate with the chain length of the
alkyl moiety of the amido-amines, which would be expected in a way that
shorter alkyl chains should correlate with lower pKa values.
Consequently the measured pKa value can only be an rough estimation of
the log Kow value. At the moment, however, there is no more suitable
method available for the determination of the log Kow of amido-amines.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Sellel veebilehel kasutatakse küpsiseid, et tagada lehe parim kasutus.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again