Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 943-535-3 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
In a study performed according to OECD TG 209, the effect of the test item on the respiration of activated sewage sludge gave a 3-hour EC50 value of > 1000 mg/L. The 3-hour NOEC was 100 mg/L.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
Following a preliminary range-finding test, activated sewage sludge was exposed to an aqueous dispersion of the test item at concentrations of 250, 500, 750 and 1000 mg/L (5 replicates) for a period of 3 hours at temperatures between 20 and 22 deg C with the addition of a synthetic sewage as a respiratory substrate. One extra concentration was added in order to determine the NOEC.
The rate of respiration was determined after 3 hours contact time and compared to data for the control and a reference item, 3,5 -dichlorophenol.
The effect of the test item on the respiration of activated sewage sludge gave a 3 -hour EC50 value of > 1000 mg/L. During the definitive test a NOEC was not achieved, however during the second range-finding test a NOEC value of 100 mg/L was observed. The reference item gave a 3-hour EC50 value of 6.5 mg/L, confidence limits 5.0-8.5 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
