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EC number: 258-964-5 | CAS number: 54079-53-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Experimental report according to guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation))
- Qualifier:
- according to guideline
- Guideline:
- other: Official Journal of the EC L 133 Part C
- Principles of method if other than guideline:
- Examination of the respiratory inhibition of activated sludge for test material
- GLP compliance:
- not specified
- Details on sampling:
- Direct weighing concentration of the animated mud in d. Prüfans. : 320.0 mg / l
- Test organisms (species):
- activated sludge
- Details on inoculum:
- activated sludge (mixed population different microorganisms)
Origin: Laboratory plant mainly with municipal sewage
Pretreatment: none - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 min
- Remarks on exposure duration:
- 30 minutes under constant ventilation
- Test temperature:
- 20 ± 2 ° C
- pH:
- 7.7
- Nominal and measured concentrations:
- 1000 , 1800 , 3200 , 5600 , 10000 mg/l
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorphenol
- Duration:
- 30 min
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Details on results:
- Based on the results obtained for test material the following toxicity to activated sludge EC 50> 10000 mg / l
- Results with reference substance (positive control):
- 3,5-Dichlorphenol EC50 = 8.8 mg/l
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The EC50 valueof test material was observed to be >10000 mg/l after 30 min of respiration inhibition test.
- Executive summary:
Effect of test material on activated sludge was evaluated according to Official Journal of the EC L 133 Part C: Biodegradability: examination of the respiratory Inhibition (largely corresponds to the test method OECD 209).A defined amount of activated sludge is made with synthetic Medium offset and measured the respiratory rate. These Respiration rate is compared with those used in test with different concentrations of the test substance be measured. The sensitivity of the activated sludge used is checked with 3,5-dichlorophenol as reference substance. Activated sludge (mixed population different microorganisms)were obtained from Laboratory plant mainly with municipal sewage. The EC50 valueof test material was observed to be >10000 mg/l after 30 min of respiration inhibition test.
Reference
Description of key information
Toxicity to microorganism:
Effect of test material on activated sludge was evaluated according to Official Journal of the EC L 133 Part C: Biodegradability: examination of the respiratory Inhibition (largely corresponds to the test method OECD 209).A defined amount of activated sludge is made with synthetic Medium offset and measured the respiratory rate. These Respiration rate is compared with those used in test with different concentrations of the test substance be measured. The sensitivity of the activated sludge used is checked with 3,5-dichlorophenol as reference substance. Activated sludge (mixed population different microorganisms)were obtained from Laboratory plant mainly with municipal sewage. The EC50 valueof test material was observed to be >10000 mg/l after 30 min of respiration inhibition test.
The test material is highly insoluble in water , the solubility was observed to be < 0.0007 mg/L , hence indicating that aquatic toxicity is unliky to occure.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 10 000 mg/L
Additional information
Toxicity to microorganism:
Effect of test material on activated sludge was evaluated according to Official Journal of the EC L 133 Part C: Biodegradability: examination of the respiratory Inhibition (largely corresponds to the test method OECD 209).A defined amount of activated sludge is made with synthetic Medium offset and measured the respiratory rate. These Respiration rate is compared with those used in test with different concentrations of the test substance be measured. The sensitivity of the activated sludge used is checked with 3,5-dichlorophenol as reference substance. Activated sludge (mixed population different microorganisms)were obtained from Laboratory plant mainly with municipal sewage. The EC50 valueof test material was observed to be >10000 mg/l after 30 min of respiration inhibition test.
The test material is highly insoluble in water , the solubility was observed to be < 0.0007 mg/L , hence indicating that aquatic toxicity is unliky to occure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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