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EC number: 257-409-4 | CAS number: 51773-49-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Mar - Apr 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: According to OECD guideline under GLP
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- Principles of method if other than guideline:
- Not relevant
- GLP compliance:
- yes
Test material
- Reference substance name:
- [2R-[2α(E),3β]]-2-[2-(3,4-dihydro-6-methoxy-1(2H)-naphthylidene)ethyl]-2-ethyl-3-hydroxycyclopentan-1-one
- EC Number:
- 257-409-4
- EC Name:
- [2R-[2α(E),3β]]-2-[2-(3,4-dihydro-6-methoxy-1(2H)-naphthylidene)ethyl]-2-ethyl-3-hydroxycyclopentan-1-one
- Cas Number:
- 51773-49-0
- Molecular formula:
- C20H26O3
- IUPAC Name:
- 17 beta-Hydroxy-3-methoxy-18-methyl-8,14-seco-1,3,5(10),9(11)-estratetraen-14-one
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): 13-Ethylsecol
- Analytical purity: 97.9%
- Lot/batch No.: 571030532
Constituent 1
Study design
- Oxygen conditions:
- anaerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 2 mg/L
- Based on:
- ThOD/L
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 2
- Sampling time:
- 28 d
- Details on results:
- The test substance attained 2 % biodegradation after 28 days.
Any other information on results incl. tables
The test substance was not found to be inhibitory to activated sewage sludge bacteria under the conditions of this test.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test substance may not be termed as readily biodegradable.
- Executive summary:
In the context of the evaluation of its potential hazard to the aquatic environment 13 -Ethylsecol (ZK 46072) was studied for ready biodegradability in the closed bottle test. The study was conducted in accordance with OECD Guideline for Testing of Chemicals No. 301 D.
The test substance was dissolved in inorganic nutrient medium (concentration: 2 mg/L) and inoculated with activated sewage sludge bacteria, was incubated in duplicate in sealed bottles for 28 days at 20 ± 1°C. On days 0, 5, 15, and 28 duplicate bottles were taken and the concentration of dissolved oxygen was measured using an oxygen probe. Percent biodegradation values were calculated by comparing the oxygen depletion with the theoretical oxygen demand. The biodegradation was also studied in bottles containing sodium benzoate alone as reference compound (3 mg/L) as well as ZK 46072 (2 mg/L) plus sodium benzoate (3 mg/L) for investigation of inhibitory effects of the test substance, all under the same conditions. The test substance showed almost no degradation. There was no indication of inhibitory effects caused by the test compound. The reference compound showed more than 70% degradation after 5 days.
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