Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 690-796-1 | CAS number: 420-16-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Documentation insufficient for assessment. Original reference is in Russian. Its translation is available but is not detailed enough. Actually this study involves several species (rats, mice and guinea-pigs) and reported results do not precise for each finding which species is concerned. In this IUCLID, all findings are reported.
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of boron fluoride
- Author:
- Kasparov AA and Kirij VG
- Year:
- 1 972
- Bibliographic source:
- Farmakol. Toksikol. 1972; 35(3): 369-372.
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Boron trifluoride
- EC Number:
- 231-569-5
- EC Name:
- Boron trifluoride
- Cas Number:
- 7637-07-2
- Molecular formula:
- BF3
- IUPAC Name:
- boron trifluoride
Constituent 1
Test animals
- Species:
- other: mouse, rat and guine-pigs
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Duration of exposure:
- > 2 - <= 4
- Remarks on duration:
- Rats and guinea-pigs were exposed for 4 h while mice were exposed for 2h.
- Concentrations:
- no data
- Details on study design:
- - Necropsy of survivors performed: yes
- Other examinations performed: clinical signs
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 1 180 mg/m³ air
- 95% CL:
- 959 - <= 1 451
- Exp. duration:
- 4 h
- Remarks on result:
- other: rats
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 3 460 mg/m³ air
- 95% CL:
- 2 900 - <= 4 350
- Exp. duration:
- 2 h
- Remarks on result:
- other: mice
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 109 mg/m³ air
- 95% CL:
- 81.5 - 146.3
- Exp. duration:
- 4 h
- Remarks on result:
- other: guinea pigs
- Mortality:
- Animals exhibiting previous findings died within 24 hours.
- Clinical signs:
- other: A marked irritation of ocular mucosa and respiratory troubles were noted. First, turmoil was observed, then an oppression phase with motor coordination troubles occurred.
- Body weight:
- Not examined
- Gross pathology:
- Dead animals exhibited mucosal cynanosis, congestion of internal organs and encephalic vessels. Moreover, lung presented an increased weight and haemorraghes. Microscopic examination confirmed lung injuries (important oedema, alveolar septa destruction. Cardiac and hepatic dystrophy were also noted. Kidneys, spleen and brain exhibited congestion.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.