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EC number: 248-607-1
CAS number: 27689-12-9
The acute oral toxicity of the test article (liquid,
lot not reported) was evaluated in male and female rats (strain
unknown). The test article was tested as received. A rangefinder was
conducted with rats (2/sex/group) receiving 1, 4, or 16 mL/kg test
article (equivalent to up to 17,600 mg/kg) via oral gavage. All rats
survived the rangefinder so a definitive study was performed. Rats in
the definitive study (5/sex/group) received water or 16 mL/kg test
article via oral gavage. The rats were observed daily for 14 days. Body
weights were recorded weekly. All animals survived. Piloerection and
hunched posture were observed shortly after dosing. Diuresis and
diarrhea was observed in 4 of 10 rats. All rats were normal by 3 days
after dosing. Body weights were normal throughout the study. Based on
the results of this study, the oral LD50 of the test article is greater
than 17,600 mg/kg.
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