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EC number: 212-782-2 | CAS number: 868-77-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09.12.2005 – 09.12.2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- adopted on 27 July 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Directive 92/69/EEC, Official Journal L 383 A 1992
- Principles of method if other than guideline:
- - Principle of test:
The vapour pressure is determined by measuring the boiling temperature of the substance at various specified pressures between roughly 10 to approx. 103 hPa. The apparatus consists of a tube with a boiling section (by electrical heating) in the lower part, a cooler in the middle part, and an outlet to a pressure regulation system in the upper part. The thermometer is placed in the vapour above the surface of the liquid. The temperature of the vapour is measured as a function of the pressure.
- Short description of test conditions: Glass apparatus with sample container, electrical heating device, cooler connected to a pressure regulating system .
Initial pressure: 6.0 hPa
Final pressure: 1025.3 hPa
- Parameters analysed: boiling temperature at different defined vapor pressures, followed by calculation of the vapour pressure at 20 °C acc. Clausius Clapeyron equation. - GLP compliance:
- yes
- Type of method:
- dynamic method
- Specific details on test material used for the study:
- Supplier: Röhm GmbH, Darmstadt, Germany
Purity: 98.84 %
Batch No. 1035092208 - Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0.08 hPa
- Remarks on result:
- other: The vapor pressure of 2-Hydroxyethylmethacrylate at 20 °C was calculated by mathematical extrapolation using the Antoine equation. based on a measured vapor pressure curve.
- Conclusions:
- The vapor pressure was calculated by mathematical extrapolation using the Clausius Clapeyron equation to be 0.08 hPa at 20 deg C.
- Executive summary:
The vapour pressure of 2-Hydroxyethyl methacrylate was determined by measuring the vapour pressure curve acc. OECD 104 between 86.6 and 211 °C . The vapour pressure at 20 °C was calculated using the Clausius Clapeyron equation and determined to be 0.08 hPa @ 20 °C.
Reference
Vapor pressure Boiling temp. Inverse temp.
[hPa] [°C] * 1000
[KE-1]
--------------------------------------------------------
6.0 86.6 2.7797
10.3 94.9 2.7170
19.8 106.3 2.6354
38.9 119.3 2.5481
80.9 134.5 2.4531
151.7 150.2 2.3621
266.6 165.7 2.2787
490.9 184.8 2.1836
747.0 199.3 2.1166
1025.3 211.5 2.0633
47.8 122.8 2.5256
--------------------------------------------------------
Description of key information
The vapour pressure of HEMA is 0.08 hPa at 20°C (OECD guideline 104/EU test method A.4; dynamic method).
Key value for chemical safety assessment
- Vapour pressure:
- 0.08 hPa
- at the temperature of:
- 20 °C
Additional information
The test result is confirmed by the calculated vapour pressure of hydroxypropyl methacrylate with EPI Suite 4.1. The calculated mean vapour pressure acc. Antoine & Grain method is 0.046 hPa @ 25 °C based on a measured boiling point of 213 °C (Röhm 2007).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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