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EC number: 215-684-8 | CAS number: 1344-00-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 Oct. 1998 - 30 Oct. 1998
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Version / remarks:
- version 07 June 1984
- Deviations:
- yes
- Remarks:
- The initial cell concentration was a about 8x higher than recommended.
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: stirring the suspensions for 24 h in 0.5 l ultrapure water, followed by filtration through paper filter.
- Eluate: Water extracts from 6250, 630, and 60 mg silicate/0.5 L, diluted to the target concentration
by additions of stock solutions needed for testing.
- Differential loading: yes
- Controls: without or with respective filtrates, but without algae
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): none
- Evidence of undissolved material (e.g. precipitate, surface film, etc): not specified - Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
- Details on test organisms:
- TEST ORGANISM
- Common name: green alga
- Strain: CHODAT
- Source (laboratory, culture collection): Pflanzenphysiol. Inst. University of Göttingen/Germany
- Age of inoculum (at test initiation): see below
- Method of cultivation: preculture 3 days prepared before test from a stock culture
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
- Post exposure observation period:
- none
- Hardness:
- not specified
- Test temperature:
- 24.9 +-0.3°C
- pH:
- Initial pH: 8.00 (control); between 8.12 and 8.58 (tests)
final pH: 10.74 - 10.76 - Dissolved oxygen:
- --
- Salinity:
- not applicable
- Nominal and measured concentrations:
- 96, 1008, and 10,000 mg/L nominal
- Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Type: open
- Material, size, headspace, fill volume: 50 ml glass cylinders
- Aeration:
- Renewal rate of test solution (frequency/flow rate): none
- Initial cells density: approx. 8 x10^4/ml
- Control end cells density: 2.83 x10^6/ml
- No. of vessels per concentration (replicates): 5
- No. of vessels per control (replicates): 7 (algal growth control), 3 (TS controls without algae)
GROWTH MEDIUM
- Standard medium used: yes
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: synthetic medium from ultrapure water
- Total organic carbon: no data
- Alkalinity: not specified
- Ca/Mg ratio: not specified
- Conductivity: not specified
OTHER TEST CONDITIONS
- Sterile test conditions: yes
- Adjustment of pH: no
- Photoperiod: continuous
- Light intensity and quality: approx. 8000 lux [>= 120 µE/(m2*sec)]
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
- Determination of cell concentrations: spectrophotometer at 578 nm after 24, 48, and 72 h
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 10 - Duration:
- 72 h
- Dose descriptor:
- NOELR
- Effect conc.:
- 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: biomass and growth rate
- Duration:
- 72 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: biomass and growth rate
- Details on results:
- - Exponential growth in the control (for algal test): yes,
After 72 h, an increase in biomass (cell numbers) at a factor of >30 was achieved at any concentration.
- Observation of abnormalities (for algal test): no particular findings specified
- Any stimulation of growth found in any treatment: slight stimulation rather than inhibition observed - Results with reference substance (positive control):
- not applicable
- Reported statistics and error estimates:
- not applicable
- Validity criteria fulfilled:
- yes
- Conclusions:
- Under the test conditions, the test substance exhibited no acute and chronic toxic effect towards the test system (Scenedesmus subspicatus CHODAT).
Reference
Description of key information
No acute and chronic aquatic toxicity identified: EL50 > 10,000 mg/L,
NOELR = 10,000 mg/L.
Key value for chemical safety assessment
Additional information
No toxicity towards algae - including the marine environment - is expected from exposure to synthetic amorphous Silicic acid, aluminum sodium salt (CAS 1344-00-9, NAS).
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