Registration Dossier
Registration Dossier
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EC number: 425-220-8 | CAS number: 5945-33-5
Endpoint summary
Administrative data
Description of key information
A 28- Day Repeated dose Oral toxicity (gavage) study in the rat.
90 day repeated dose + reprotox parameters
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
- Study duration:
- chronic
- Species:
- rat
Additional information
A 28 days subchronic test was performed with fyrolflex BDP. Oral administration of Fyrolflex BDP to rats for
28 consecutive days at dose level of 1000mg/kg/day produced no treatment related changes in the parameters measured. The NOAEL is therefore 1000mg/kg/day. Robust summary of the study is attached to the relevant endpoint records
In addition a 90 day repeated dose toxicity study was performed, including reprotox parameters, the NOAEL was here also 1000 mg/kg/day, and no reprotoxicity effects were found.
Justification for classification or non-classification
The substance should not be classifided based on NOAEL 1000mg/kg/day
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