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Diss Factsheets
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EC number: 248-666-3 | CAS number: 27813-02-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- no
- Oxygen conditions:
- not specified
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- ca. 28 d
- Details on study design:
- Measurement and analysis:
Biochemical oxygen demand
Total organic carbon analyzer
Gas chromatography
Concentration: 100 mg/L
Concentration of activated sludge: 30%
Volume of test solution: 300 mL
Cultivation temperature: 25 deg C - Reference substance:
- not specified
- Key result
- Parameter:
- other: BOD
- Value:
- 81
- Sampling time:
- 28 d
- Remarks on result:
- other: 10 days window where not available to the subscriber, it is not applicable for the MITI test
- Results with reference substance:
- Control substance(BOD)
Aniline (Lot No. SE-31230, Showa Chemical Industry Co.,Ltd. ,reagent grade)
55% after 7 days,
65% after 14 days - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test substance was determined to be readily biodegradable with a BOD percent biodegradation of 81% after 28 days.
- Executive summary:
In a valid guideline study (MITI-I, OECD TG 301 C), the average overall biodegradation of the substance 2-hydroxypropyl methacrylate was 81 % (ultimate biodegradation as determined by biochemical oxygen demand) and 100 % (primary degradation as determined by specific analysis (GC)). (Remark: The 10-day window concept does not apply to the MITI-Test)
Reference
Percent biodegradation
BOD: 81%
TOC: 93%
GC: 100%
Test Conditions
Conditions of cultivation | value | unit |
Concentration of test substance | 100 | mg/L |
Concentration of activated sludge [suspended solid] | 30 | mg/L |
Volume of test solution | 300 | mL |
Cultivation temperature | 25 | °C |
Cultivation duration | 28 | days |
Results
| percentage biodegradation (%) | average | ||
BOD | 82 | 82 | 80 | 81 |
TOC | 92 | 93 | 92 | 93 |
GC | 100 | 100 | 100 | 100 |
Abreviations
BOD: Biochemical oxygen demand
TOC: Total organic carbon analyzer
GC: Gas chromatography
Description of key information
In a valid guideline study (MITI-I, OECD TG 301 C), the average overall biodegradation of the substance 2-hydroxypropyl methacrylate was 81 % (ultimate biodegradation as determined by biochemical oxygen demand) and 100 % (primary degradation as determined by specific analysis (GC)). (Remark: The 10-day window concept does not apply to the MITI-Test)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Additional information is available from a static activated sludge test OECD 301 E. The biodegradation was measured by DOC-elimination. The biodegradation was 94.2% after 28 days. A biodegradation of about 80 % was achieved within the 10 day-window. In this test hydroxypropyl methacrylate was readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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