Registration Dossier
Registration Dossier
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EC number: 500-035-6 | CAS number: 25214-63-5 (>1 <8.5 mol PO)
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Ethylenediamine, propoxylated was negative in three assays:
- bacterial reverse mutation assay
- in vitro HPRT cell mutation assay (OECD 476)
- in vitro micronucleus test (OECD 487)
In addition, the results for one further assay from Ethylenediamine, ethoxylated and propoxylated, was also negative.
- Negative result read across from an in-vitro chromosome aberration test with Chinese Hamster V79 cells
Short description of key information:
Three in vitro mutagenicity tests using different end points were all negative. Therefore further testing is not required.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
The results from in-vitro testing of genetic toxicity do not warrant classification according to EU GHS.
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