Registration Dossier
Registration Dossier
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EC number: 606-728-0 | CAS number: 212322-56-0
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 05 October 2004 - 23 November 2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- ethyl 3-{1-[3-amino-4-(methylamino)phenyl]-N-(pyridin-2-yl)formamido}propanoate
- EC Number:
- 606-728-0
- Cas Number:
- 212322-56-0
- Molecular formula:
- C18 H22 N4 O3
- IUPAC Name:
- ethyl 3-{1-[3-amino-4-(methylamino)phenyl]-N-(pyridin-2-yl)formamido}propanoate
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- The test item was stored in a tightly closed vessel at room temperature under dry conditions.The test was performed at room temperature (21+/-2 deg Celsius) without direct lighting. The concentration of suspended solids (Inoculum) in the test flasks was 24.5 mg/l. Duration of the test was 29 days.
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 12
- Sampling time:
- 28 d
- Details on results:
- The test item can be considered as "not readily biodegradable".
The degree of biodegradation reached 12% after 28 days.
The 10d-window began on day 16, at its end, 10% were reached, not reaching the pass level of 60% given in the OECD guideline.
The abiotic degradation reached 21%.
Applicant's summary and conclusion
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- BIBR 1048 Diamin is not readily biodegradable following OECD 301B/EU C.4-C.
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