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Diss Factsheets
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EC number: 622-542-2 | CAS number: 3891-98-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
Water solubility was investigated using a slow-stir method (Letinski et al., 2016) combined with SPME and GC-MS analysis. This is a more reliable and accurate method for the determination of the water solubility of poorly soluble hydrocarbons. The measured water solubility was 0.25 µg/L, which is supported by QSAR predicted water solubility values in the range 1.3 and 4.4 µg/L.
Key value for chemical safety assessment
- Water solubility:
- 0.25 µg/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of Farnesane was tested experimentally as part of the ecotoxicity studies (Wildlife International 2012). In these ecotoxicity studies, acetone was used as the solvent because farnesane was known to be highly insoluble; solvents are used in eco toxicity studies to allow tests of the possible toxicity of a substance that is not readily soluble in water. The result of such a test provides an indication of the possible toxicity of the substance if it were able to dissolve and achieve a certain concentration. However, these are not naturally occurring conditions and hence water solubility and exposure are overestimated. Similarly, if a solubility test is conducted using a solvent the results are not indicative of the true solubility of the substance. Therefore, the water solubility results obtained from the ecotoxicity studies do not reflect the true water solubility of farnesane.
The slow-stir method, combined with SPME and GC-MS analysis used by Letinski et al. (2016) is considered a more reliable and accurate method for determination of the true water solubility of poorly soluble hydrocarbons. The measured water solubility was 0.25 µg/L, which is supported by QSAR predicted water solubility values in the range 1.3 and 4.4 µg/L. Farnesane is therefore considered essentially insoluble in water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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