Registration Dossier
Registration Dossier
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EC number: 233-651-6 | CAS number: 10291-28-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Mutagenic activity of the test item was investigated in various reliable guideline studies performed in Salmonella typhymurium strains 1535, 1537, 98, 100 and 1538 as well as Escherichia coli WP2 uvrA with and without metabolic activation (induced rat liver S9-mix) at concentrations of 4 to 10000 µg/plate. Under the conditions tested the test compound did not cause a significant increase in the number of revertant colonies and no dose dependent effects were observed.
Therefore the test item is not considered mutagenic under the tested conditions in this reverse bacterial mutation assay.
Short description of key information:
The test item did not exert any mutagenic activity in the reverse bacterial mutation assay.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Due to the negative mutagenic properties of the test item in the experimental studies (reverse bacterial mutation assay) the test item has not to be classified for mutagenic activity.
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