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EC number: 205-124-0 | CAS number: 133-91-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish :
No. of predictions done for short term fish toxicity endpoints having Klimish rating 2
The summary of the results are presented below:
Sr. No |
Endpoint name |
Value |
Effect |
Species |
Source |
1 |
LC50 |
6.449672699 mg/l |
Mortality |
Oryzias latipes |
SSS QSAR |
2 |
LC50 |
5.768873215 mg/l |
Mortality |
Pimephales promelas |
SSS QSAR |
3 |
LC50 |
3.296432972 mg/L |
Mortality |
Cyprinodon variegatus |
SSS QSAR |
4 |
LC50 |
7.42 mg/L |
Mortality |
Fish |
ECOSAR |
5 |
LC50 |
10 mg/L |
Mortality |
Ptychocheilus oregonensis : Northern Squawfish |
ECOTOX |
After comparing the short term toxicity values from predictions done in QSAR rtoolbox 3.1 & estimated data from ECOSAR & ECOTOX. it was estimated values varies from 3.296432972 to 10 mg/l . But the BCF value of 3,5-diiodosalicylic acid reported was not >= 500 as well as the substance was found to be rapidly degradable. Since the additional criteria mentioned in the CLP regulation related to BCF, biodegradability and Log Kow is not satisfied thus the substance has not been considered for aquatic toxicity classification. It is concluded that 3,5-diiodosalicylic acid does not exhibit short term toxicity to fish.
Short-term toxicity to aquatic invertebrates :
No. of predictions done for short term Aquatic invertebrate endpoints having Klimish rating 2
The summary of the results are presented below:
Sr. No |
Endpoint name |
Value |
Effect |
Species |
Source |
1 |
EC50 |
7.907 mg/L |
Mobility |
Daphnia magna |
SSS QSAR |
2 |
LC50 |
7.045 mg/L |
Mortality |
Daphnia magna |
ECOSAR Version 1.10 |
3 |
EC50 |
1.889201522 mg/L |
Intoxication |
Daphnia magna |
SSS QSAR |
After comparing the short term toxicity values from predictions & estimated calculation. It was found to be varies from 1.889201522 to 7.097 mg/l. But the BCF value of 3,5-diiodosalicylic acid reported was not >= 500 as well as the substance was found to be rapidly degradable Thus considering only the value from CLP Criteria for aquatic classification of the substance , it is concluded that 3,5-diiodosalicylic acid does not exhibit short term toxicity to Aquatic invertebrate (Daphnia magna).
Toxicity to aquatic algae and cyanobacteria:-
No. of predictions done for short termtoxicity to algae and cynobacteriaendpoints having Klimish rating 2.
The summary of the results are presented below:
Sr. No |
Endpoint name |
Value |
Effect |
Species |
Source |
1 |
EC50 |
22.351 mg/l |
Growth rate |
Selenastrum capricornutum (new name: Pseudokirchnerella subca |
SSS QSAR |
2 |
EC50 |
25.221 mg/L |
-- --- --- |
Green Algae |
ECOSAR Version 1.10 |
3 |
EC50 |
3.954859257 mg/L |
Growth rate |
Selenastrum capricornutum (new name: Pseudokirchne |
SSS QSAR |
4 |
EC50 |
7.045009136 mg/L |
Growth rate |
Pseudokirchneriella subcapitata |
SSS QSAR |
After comparing the Toxicity to algae and cynobacteria values from QSAR 3.1 predictions & estimated calculations. it was found to be varies from 3.954 to 25.221 mg/L The BCF value of 3, 5-diiodosalicylic acid reported was not >= 500 as well as the substance were found to be rapidly degradable. Since the additional criteria mentioned in the CLP regulation related to BCF, biodegradability and Log Kow is not satisfied thus the substance has not been considered for aquatic toxicity classification.
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