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Diss Factsheets
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EC number: 903-945-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Based on experimental data on each constituent, the reaction mass is considered to have a 3h EC50 of 660 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 660 mg/L
Additional information
No data on toxicity to microorganisms is available on the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA).
The following data are available on each constituent:
For CDFA, a 3-hour activated sludge respiration inhibition test was performed using activated sludge from a domestic waste treatment plant according to the OECD Testing Guideline 209 and under GLP conditions. The microorganisms were exposed to five concentrations of the test substance at nominal concentrations of 100, 200, 400, 800 and 1600 mg/L. The respiration rate, expressed as oxygen consumption by the microbes in mg O2 per liter per hour, was measured under defined conditions following the 3-hour exposure period. Inhibition values were calculated by comparing test respiration rates to negative control rates.
EC50 values were calculated by regression analysis. The result indicated that under valid test conditions the 3 h-EC50 value of 3, 5-dichlorophenol was 6.98mg/L. The 3 h-EC50 value of the test substance Chlorodifluoroacetic acid was 660mg/L.
For TFA, the influence of the test item Sodium trifluoroacetate on the activated sludge was evaluated by measuring the respiration rate under defined conditions, according to EU Method C.11 and OECD 209 Guidelines. The respiration rate (oxygen consumption) of an aerobic activated sludge fed with a standard amount of synthetic sewage was measured in the presence of various concentrations of the test item (10, 32, 100, 320 and 1000 mg/L) after an incubation period of 3 hours. The inhibition of the bacterial respiration activity was in the range of 3.2 to 9.7% for the test concentrations of 10 to 1000 mg/L. Therefore, the NOEC of Sodium trifluoroacetate was established above 1000 mg/L (832 mg TFA/L). The positive control 3,5 -Dichlorophenol was tested in the same way as the test item with nominal concentrations of 3.2, 10 and 32 mg/L. The 3 -hour EC50 was found to be 12.0 mg/L thus laying in the range of 5 -30 mg/L recommended by the test guidelines. The result confirms the suitability of the activated sludge used.
Considering that the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA) is mainly composed of CDFA, the reaction mass is considered to have a 3h EC50 value for microorganisms of 660 mg/L.
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