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EC number: 931-210-9 | CAS number: 1266534-73-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
NOEC(21d) = 32 mg/L (RA Zeolite cuboidal)
Key value for chemical safety assessment
Additional information
No data for long-term toxicity to aquatic invertebrates are available for the target substance Aluminium silicate and titanium oxide matrix doted with vanadium, nickel, and antimony. Therefore, data from the analogue approach source substance Zeolite, cuboidal, crystalline, synthetic, non-fibrous catalysts were applied to cover the endpoint long-term toxicity to aquatic invetebrates for the target substance.
The chronic toxicity study on Daphnia magna with Zeolite, cuboidal, crystalline, synthetic, non-fibrous, was conducted according to OECD 211 under GLP conditions (Paulus 2005, RL2). A saturated solution was prepared by shaking a nominal load of 1000 mg/L with deionised water for 24 hours, followed by membrane filtration (pore size not given). Then different dilutions of the filtered test solution were tested (10, 32, 100, 320 and 1000 mg/L). The mean offspring number was significant reduced at 100 mg/L and higher concentrations, mortality was observed in the two highest concentrations. Therefore, a NOEC(21d) = 32 mg/L was stated.
Generally, an indirect, physical effect of Zeolite, cuboidal, crystalline, synthetic, non-fibrous has to be assumed for daphnids: they are not able to distinguish food particles because of their nutritional quality (DeMott, 1986), in contrast to e.g. copepods or rotifers. Daphnids filter particles within a distinct size fraction defined by morphological parameters (Geller and Müller, 1981; Gophen and Geller, 1984), which is 1 to 100 µm for Daphnia magna. Zeolite, cuboidal, crystalline, synthetic, non-fibrous with an aggregate size within a range of about 1 to 20 µm is therefore exactly within this size spectrum, implying that daphnids may mainly ingest cuboidal Zeolite in turbid suspensions or will delete the complete filtered particles with their furca claw prior to ingestion and starve.
Therfore it can be presumed, that the above described effect is due to physical effects. Up to the limit of water solubility, no effects could be observed.
A further study with Zeolite, cuboidal, crystalline, synthetic, non-fibrous was available (not shown here), which supported the results from the discussed key study.
Additional data for long-term toxicity to aquatic invertebrates are available for the following source substance which serve as potential data source for the analogue approach of Aluminium silicate and titanium oxide matrix doted with vanadium, nickel, and antimony:
- Source chemical 6 - Kaolin:
NOEC(30 d) = 100 mg/L, Oncorhynchus mykiss; Hashimoto et al. 1986
In accordance with the target substance, the available data for this source substance also provide a low potential for long-term toxicity to aquatic invertebrates.
The respective references for the source substance data can be found in the data matrix of the justification for the analogue approach, which can be found either in the CSR or as attachment in Iuclid section 13.
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