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Diss Factsheets
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EC number: 402-600-1 | CAS number: 765-12-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Acute oral toxicity: LD50: > 2000 mg/kg bw
Acute dermal toxicity: LD50: > 4000 mg/kg bw
Acute inhalative toxicity: no data
Key value for chemical safety assessment
Additional information
Oral
For the investigation of the acute oral toxicity of Triethylenglycoldivinylether, three males and three females Wistar rats received a single oral dose of the test material preparation in olive oil at a dose level of 2000 mg/kg bw (GLP guideline study; BASF 1997). Signs of toxicity noted comprised impaired or poor general state, dyspnoea, apathy, abdominal position, staggering, ataxia, atonia, paresis and exsiccosis. The animals appeared normal 1 day after application. The expected body weight gain was observed in the course of the study. No mortality occurred. No abnormalities were noted at necropsy of animals sacrificed at the end of the study. Under the conditions of this study, the LD50 of Triethylenglycoldivinylether after oral application was found to be greater than 2000 mg/kg bw.
Dermal
For the determination of the acute dermal toxicity of Triethylenglycoldivinylether, the test material was applied undiluted at a dose level of 4000 mg/kg bw to the clipped epidermis (dorsal and dorsolateral parts of the trunk) of five male and five female rats and covered by a semi-occlusive dressing for 24 hours. Systemic signs of toxicity were not noted. A very slight erythema was observed in two male and two female animals 1 day after application. No abnormalities were noted at necropsy of animals sacrificed at the end of the study. No mortality occurred. Under the conditions of this study, the LD50 of Triethylenglycoldivinylether after dermal application was found to be greater than 4000 mg/kg bw.
Inhalative
The inhalative route is not a relevant route of exposure due to the low vapor pressure (0.0042 hPa) and use (no formation of an inhalable aerosol).
Justification for classification or non-classification
Classification for acute toxicity is not warranted according to the criteria of EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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