Registration Dossier
Registration Dossier
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EC number: 202-852-0 | CAS number: 100-43-6
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
4VP is likely to be absorbed via the gastrointestinal tract, distributed in the water compartment of the body, and excreted via the kidneys with or without metabolism. Bioaccumulation and deposition in fat or breast milk is not likely.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
- Absorption rate - oral (%):
- 100
- Absorption rate - dermal (%):
- 100
- Absorption rate - inhalation (%):
- 100
Additional information
Assessment of the toxicokinetic behaviour of 2VP, and by analogue similarity of the common functional group, 4VP, was undertaken to the extent that can be derived from the relevant available information. Critical data included is low molecular weight, high water solubility and low octanol/water partitioning. These data suggest that 4VP is likely to be absorbed via the gastrointestinal tract, distributed in the water compartment of the body, and excreted via the kidneys with or without metabolism. At the least, phase II conjugation enzymes may act upon absorbed 4VP. Bioaccumulation and deposition in fat or breast milk is not likely.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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