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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary references

Data source

Materials and methods

Results and discussion

Effect levels
Remarks on result:
other: see Any Other Information

Any other information on results incl. tables

Acute inhalation

Data lacking

No valid studies are available. The available study gets a K4 since no original references are available only secondary references. No LD50 is available.

 

Classification and Labeling

No LD50 available, data is not sufficient for C&L purposes.

No deaths after 8 hour exposure to saturated vapor.

Union carbide corp. unpublished data. Cited in[Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4687]

Narcosis, but not death, was observed in mice inhaling concentrations close to saturation.

The threshold for an irritating effect in man was 220 mg/m3.

 

Bukhalovskii, A. A. & Shugaev, B. B. (1976). Toksichnost i gigienicheskoe normirovanie izoforona, digidroizoforona

i dimetilfenilkarbinola.Promyshlennost Sillleticheskogo Kauchuka1976 (2), 4. Cited in:Food and Chemical Toxicology. Vol. 20, Pg. 675, 1982

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
No valid studies are available. The available study gets a K4 since no original references are available only secondary references. No LD50 is available, data is not sufficient for C&L purposes.
Executive summary:

No valid studies are available. The available study gets a K4 since no original references are available only secondary references. No LD50 is available, data is not sufficient for C&L purposes.