Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 800-984-9 | CAS number: 1428547-35-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- Koc at 20 °C:
- 34 850
Additional information
The registered substance is a salt composed of a primary alkyl amine and a fatty acid. Both elements present a long hydrogenated (saturated) carbon chains (16 to 18 carbon atoms). As mentioned in the summary Aquatic Toxicity, it is relevant to use the available ecotoxicity data of the primary alkl amine by a read-across approach for the salt. Therefore, the data of adsoption/desorption available for the primary alkyl amine were used to complete this endpoint for the registered substance.
Adsorption/desorption of the primary alkyl amines
Due to the surface-active properties, long-chained alkyl amines adsorb strongly onto the solid phase of soil and sediments. The determination of a Koc from log Kow is not opportune, because the common equations for Koc derivation are not valid for both ionic and surface active substances.
Slangen (2000) studied the adsorption behaviour of 1-14C-labelled n-octadecylamine in a batch equilibrium experiment according OECD 106. Two soils collected in UK (Cranfield 164 soil, 21.8% clay, 6.6% organic matter, silt loam; Cranfield 266 soil, 50.2% clay, 2.6% organic matter, clay), one sediment collected in The Netherlands (18.7% clay, 4.1% organic matter, silt loam) and a sewage sludge (45.9% clay, 51.9% organic matter, silty clay) were used, encompassing a range of % clay and organic material. The test substance adsorbed partially onto the container walls which was considered for the determination of the adsorption coefficients. Adsorption kinetics was determined by measurements at different sampling times (up to 24 h), an equilibrium was reached after 3 hours. Desorption occurred to a lesser extent than adsorption: for Cranfield 164 soil 24.4% desorption after 47 hours and 24.2% after 166 hours were determined, while desorption for Cranfield 266 soil was 13.7% after 47 hours and 19.1% after 166 hours. The Freundlich adsorption isotherms were determined to:
Table:Freundlich adsorption isotherms determined by Slangen (2000):
Compartment |
KFAds (µg1-1/n(cm3)1/ng-1) |
1/n |
Soil: Cranfield 164 silt loam |
3065 |
1.5384 |
Soil: Cranfield 266 clay |
30053 |
1.8897 |
Sediment: Oostvaardersplassen silt loam |
6433 |
1.4478 |
Sewage sludge: DB1 silty clay |
821 |
1.0322 |
Apparently, the sorption onto Cranfield 266 soil is much higher than to Cranfield 164 despite of the higher organic matter content in Cranfield 164 soil. This can be explained that ionic interactions play a more important role than hydrophobic partitioning with organic matter. Alkyl ammonium ions can interact with the surface of mineral particles or with negative charges of humic substances. The influence of the chain length on the sorption behaviour is therefore expected to be low, and the experimental results obtained in the test with octadecyl amine can be taken as representative for the other products. As well, an influence of the double bond (in octadecenylamine) onto sorption is not expected.
The adsorption isotherms determined by Slangen (2000) are non-linear. The distribution constants for soils and sediment decrease dramatically as the concentrations decrease. The lowest aquatic equilibrium concentration in the experiment (5 µg/l) is more than one order of magnitude higher than the calculated PEC values. For example, with the isotherm determined for the sediment and an aquatic concentration of 10 ng/L, a Kp value of 37 L/kg is calculated, which is far below the constants determined in the experiment (707 – 3140 l/kg). Apparently, extrapolation to low concentrations would lead to unrealistic results.
According to the Danish EPA (2004) a more reliable method of extrapolation is to use the data originating from the lowest measured concentrations and to assume that the coefficient remains constant at lower concentrations. At the 2 lowest concentrations, values of 707 and 687 L/kg were experimentally determined, the mean value (697 L/kg) is used for the exposure assessment.
The mean values for the two soils are 252 and 342 l/kg, respectively. Because there is no principal difference between soil and sediments on respect to the sorption properties, as a worst case approach the value for sediment is also used for soils and suspended particles.
For the adsorption onto sludge, values of 687 and 674 L/kg were determined for the 2 lowest concentrations. The mean value (680 L/kg) is used for the exposure calculation.
In the table below, the distribution constants used in this assessment are summarized:
Table:Distribution constants for primary alkyl amines
Kpsoil |
697 l.kg-1 |
Ksoil-water |
1050 m3.m-3 |
Kpsusp |
697 l.kg-1 |
Ksusp-water |
175 m3.m-3 |
Kpsed |
697 l.kg-1 |
Ksed-water |
349 m3.m-3 |
Kpsludge |
680 l.kg-1 |
|
|
With a Kpsuspof 697 l/kg and a concentration of 15 mg/l suspended matter in surface waters, the adsorbed fraction is calculated as 1.0%.
[LogKoc: 4.54]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.