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Diss Factsheets
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EC number: 266-885-2 | CAS number: 67674-46-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The ready biodegradability of Methyl Pamplemousse was determined by the Manometric Respiratory Test according to OECD Guidelines No 301F. Under the conditions of the study, the test substance underwent -3 % biodegradation after 28 days. Thus, the test substance should be regarded as not readily biodegradable according to this test.
The inherent biodegradability of Methyl Pamplemousse was determined by the Manometric Respirometry Test according to the OECD Guidelines for Testing of Chemicals, Method No. 302C. The repeatability between the two replicates was poor. At day 7 the measured biodegradation was 8 and 19%, and at the end of the test -5 and 15%. However, it can be inferred from the results that Methyl Pamplemousse undergoes no significant (i.e. below 20%) biodegradation after 32 days in the test conditions. Thus, Methyl Pamplemousse should be regarded as not inherently biodegradable according to this test.
Based on the above two tests, the conclusion for the chemical safety assessment is that no biodegradation was observed.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Intrinsic shortcomings associated with the above screening tests have been reported (Roberts et al. 2009, Influence of inoculum source in the biodegradability of Propanolol and Atenolol, poster presentation SETAC-Europe meeting Göteburg, Sweden 31 May - 04 June 2009; ECETOC Workshop Report No. 10 - Workshop on biodegradation and persistence, 26 - 27 June 2007, Holmes Chapel, UK), including low diversity in microbial populations of the inoculum, over-exaggerated test concentrations compared to those likely to occur in the environment under realistic use conditions, absence of light, and lack of aeration. The use of high test concentrations in these studies may lead to reduced bioavailability and, in certain cases, can result in either subtle or marked inhibition effects on the microbial population present. As such, these screening tests are considered to represent an extreme worst case situation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.