Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1993

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
Deviations:
not specified
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Octanoic acid, compound with octylamine (1:1)
EC Number:
241-477-7
EC Name:
Octanoic acid, compound with octylamine (1:1)
Cas Number:
17463-34-2
Molecular formula:
C8H19N.C8H16O2
IUPAC Name:
octan-1-amine; octanoic acid
Details on test material:
- Analytical purity: 100%
- CAS-No: 17463-34-2

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
activated sludge of a predominantly domestic sewage
Details on inoculum:
- Name and location of sewage treatment plant where inoculum was collected: Municipal sewage treatment plant in Frankfurt-Sindlingen
- Pretreatment: according to guideline
- Initial biomass concentration: 1600 mg/l dry weight

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h

Test conditions

Test temperature:
20 ± 2 °C
pH:
7.2 ± 0.2
Nominal and measured concentrations:
62.5-1000mg/l
Details on test conditions:
Test medium: Composition according to guideline

Reference substance (positive control):
yes
Remarks:
3,5-Dichlorphenol (5, 20, 30 mg/l)

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
other: EC20
Effect conc.:
205 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
442.9 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Duration:
3 h
Dose descriptor:
other: EC80
Effect conc.:
956.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration

Applicant's summary and conclusion

Conclusions:
The 3 hour EC50 for microorganism of the test item Caprylamine caprylate was 442,9 mg/L.
Executive summary:

The respiration inhibition of the test item was tested in a study similar to OECD Guideline for Testing of Chemicals 209. The 3 hour EC50 for microorganism was 442,9 mg/L.