Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
> 200 - < 2 000 mg/kg bw
Quality of whole database:
Source1: data from Supplier (Test method OECD 423)
Source2: Journal of Medicinal Chemistry. Vol. 21, Pg. 906, 1978
Reliability 2
LD50 oral mouse > 300 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
1 200 mg/kg bw
Quality of whole database:
LD50 rat: 1200 mg/kg bw
Source: Aerospace Medical Research Laboratory Report. Vol. TR-74-78, Pg. 1974

LD50 rabbit: 1250 mg/kg bw
Food and Cosmetics Toxicology. Vol. 17, Pg. 723, 1979.

Experimental data on the similar substance Bromobenzonitrile CAS 100-47-0

Additional information

Justification for classification or non-classification