Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 237-198-5 | CAS number: 13684-56-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Surface tension
Administrative data
Link to relevant study record(s)
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-09-04 to 2012-12-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- ring method
- Key result
- Surface tension:
- 71.5 mN/m
- Temp.:
- 20 °C
- Remarks on result:
- other: 90% saturated solution, dissolved in 7 mmol acetic acid to aid dissolution
- Conclusions:
- 72.39 mN/m at 20°C
- Executive summary:
Test Guidelines: OECD Guideline 115 European Commission Council Regulation (EC) No 440/2008, Annex, Part A, method A.5. US EPA OCSPP Not Applicable
Results
The surface tension of an aqueous solution of Desmedipham, was determined according to the European Commission Council Regulation (EC) No. 440/2008, Annex, Part A, A.5. and OECD Test Guideline 115, ring method.
The solubility of the test item in distilled water is below 1 g/L (5.6 mg/L at 20 °C). Therefore, according to the OECD and EEC guidelines, the concentration of the test solutions used should be 90% of the saturation solubility.
Due to the low water solubility some of the eluate fractions from the water solubility study were diluted to be used for the determination of the surface tension. The concentrations of the diluted solutions used were determined by HPLC analyses to be 5.1 mg/L and 4.9 mg/L respectively (approx. 90 % of the saturation concentration).
Due to the lack of stability of the test item in solutions with pH values > pH 4, the test was performed in distilled water acidified with small amounts of acetic acid. The acetic acid concentration of the solutions being measured was 7.0 mmol/L.
Two independent determinations were performed.
Surface tension of desmedipham, at 20 ± 0.5°C:
Blank solution (acetic acid, c = 7.0 mmol/L Desmedipham, stabilised in acetic acid solution (7.0 mmol/L acetic acid) c = 5.0 mg/L (mean) σ = 71.8 mN/m σ = 71.5 mN/m The surface tension of desmedipham, stabilised in acetic acid solution (c = 7.0 mmol/L) was 71.5 mN/nm and is therefore of the same order of magnitude as the surface tension of pure distilled water (σ = 72.75 mN/m).
Reference
The surface tension of an aqueous solution of Desmedipham, was determined according to the European Commission Council Regulation (EC) No. 440/2008, Annex, Part A, A.5. and OECD Test Guideline 115, ring method. The solubility of the test item in distilled water is below 1 g/L (5.6 mg/L at 20 °C, Ref. 1). Therefore, according to the OECD and EEC guidelines, the concentration of the test solutions used should be 90% of the saturation solubility. Due to the low water solubility some of the eluate fractions from the water solubility study (Ref. 1) were diluted to be used for the determination of the surface tension. The concentrations of the diluted solutions used were determined by HPLC analyses to be 5.1 mg/L and 4.9 mg/L respectively (approx. 90 % of the saturation concentration). Due to the lack of stability of the test item in solutions with pH values > pH 4 (Ref. 2), the test was performed in distilled water acidified with small amounts of acetic acid. The acetic acid concentration of the solutions being measured was 7.0 mmol/L.
Two independent determinations were performed in Firgure 1.
Surface tension of desmedipham (AE B038107), at 20 ± 0.5°C:
Description of key information
The surface tension of desmedipham, stabilised in acetic acid solution (c = 7.0 mmol/L) was 71.5 mN/n
Key value for chemical safety assessment
- Surface tension:
- 72.39
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.