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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Between 06 December 1999 and 07 December 1999.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
Method A4 specified in Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
Deviations:
not specified
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance
Specific details on test material used for the study:
No further details specified in the study report.
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa

Run 1

Temperature

(°C)

Temperature

(K)

Reciprocal temperature

(K-1)

Mass difference

(μg)

Mass difference

(kg)

Vapour pressure

(Pa)

Log10Vp

129

402.15

0.002486634

42.92

4.292E-08

0.059583956

-1.224870665

128

401.15

0.002492833

37.08

3.708E-08

0.051476540

-1.288390653

127

400.15

0.002399063

34.04

3.404E-08

0.047256241

-1.325540827

126

399.15

0.002505324

33.93

3.393E-08

0.047103533

-1.326946519

125

398.15

0.002511616

24.52

2.452E-08

0.034040042

-1.468009913

124

397.15

0.002517940

22.43

2.243E-08

0.031138587

-1.506701105

123

396.15

0.002524296

21.14

2.114E-08

0.029347736

-1.532425396

122

396.15

0.002530685

21.93

2.193E-08

0.030444458

-1.516491747

121

394.15

0.002537105

20.84

2.084E-08

0.028931259

-1.538632664

120

393.15

0.002543558

17.60

1.760E-08

0.024433309

-1.612017711

119

392.15

0.002550045

16.92

1.692E-08

0.023489295

-1.629130020

118

391.15

0.002556564

13.78

1.378E-08

0.019130170

-1.718281161

117

390.15

0.002563117

11.71

1.172E-08

0.016270363

-1.788602767

116

389.15

0.002569703

10.68

1.968E-08

0.014826576

-1.828959126

115

388.15

0.002576324

10.09

1.009E-08

0.014007505

-1.853639212

114

387.15

0.002582978

8.96

8.960E-09

0.012438776

-1.905222369

113

386.15

0.002589667

7.73

7.730E-09

0.010731220

-1.969350885

112

385.15

0.002596391

7.11

7.110E-09

0.009870502

-2.005660778

111

384.15

0.002603150

7.31

7.310E-09

0.010148153

-1.993613002

110

383.15

0.002609944

6.10

6.100E-09

0.008468363

-2.072200544

109

382.15

0.002616774

5.81

5.819E-09

0.008065769

-2.093354246

108

381.15

0.002623639

5.44

5.440E-09

0.007552114

-2.121931479

107

380.15

0.002630541

4.20

4.200E-09

0.005830676

-2.234281088

106

379.15

0.002637479

4.10

4.100E-09

0.005691850

-2.244746522

105

378.15

0.002644453

3.76

3.760E-09

0.005219843

-2.282342534

104

377.15

0.002651465

2.87

2.870E-09

0.003984295

-2.399648482

103

376.15

0.002658514

2.46

2.460E-09

0.003415110

-2.466595272

102

375.15

0.002665600

2.16

2.160E-09

0.002998633

-2.523976628

101

374.15

0.002672725

2.00

2.000E-08

0.002776512

-2.556500383

A plot of Log10(vapour Pressure (Pa)) versus reciprocal temperature (1/T(K)) for run 1 give the following statistical data using an unweighted least squares treatment.

 

Slope -6915.705

Standard deviation in slope 117.242

 

Intercept 15.692

Standard deviation in intercept 0.302

 

The results obtained indicate the following vapour pressure relationship.

Log10(Vp (Pa)) = -6.915.705/temp(K) + 15.962

 

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -7.233.

 

Run 2

Temperature

(°C)

Temperature

(K)

Reciprocal temperature

(K-1)

Mass difference

(μg)

Mass difference

(kg)

Vapour pressure

(Pa)

Log10Vp

126

399.15

0.002505324

18.54

1.854E-08

0.002578270

-1.589420649

127

400.15

0.002499063

21.31

2.131E-08

0.029583740

-1.528946929

128

401.15

0.002492833

23.38

2.338E-08

0.032457430

-1.488685872

129

402.15

0.002486634

26.01

2.601E-08

0.036108544

-1.442390027

130

403.15

0.002480466

29.25

2.925E-08

0.020606494

-1.391404508

131

404.15

0.002474329

32.14

3.214E-08

0.044618554

-1.350484506

132

405.15

0.002468222

35.27

2.527E-08

0.048963796

-1.310124919

133

406.15

0.002462145

38.53

3.853E-08

0.053489511

-1.271731370

134

407.15

0.002456097

43.10

4.310E-08

0.059833842

-1.223053109

135

408.15

0.002450080

45.86

4.586E-08

0.063665429

-1.196096328

136

409.15

0.002444091

48.15

4.815E-08

0.066844536

-1.1749340987

137

410.15

0.002438132

54.29

5.429E-08

0.075368429

-1.122810537

138

411.15

0.002432202

59.84

5.984E-08

0.083073251

-1.080538794

139

412.15

0.002426301

61.51

6.151E-08

0.085391639

-1.068584652

140

413.15

0.002420428

66.16

6.616E-08

0.091847030

-1.036934882

141

414.15

0.002414584

75.26

7.526E-08

0.104480162

-0.980966165

142

415.15

0.002408768

79.28

7.928E-08

0.110060951

-0.958366737

143

416.15

0.002402980

85.04

8.504E-09

0.118057307

-0.927907127

144

417.15

0.002397219

92.60

9.260E-08

0.128552524

-0.890919392

145

418.15

0.002391486

101.64

1.016E-07

0.141102360

-0.850465722

146

419.15

0.002385781

107.23

1.072E-07

0.148862712

-0.827214073

147

420.15

0.002380102

119.23

1.192E-07

0.165521787

-0.781144835

A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 2 gives the following statistical data using an unweighted least squares treatment.

 

Slop -6211.851

Standard deviation in slope 82.522

 

Intercept 14.009

Standard deviation in intercept 0.202

 

The results obtained indicate the following vapour pressure relationship

Log10(Vp (Pa)) = 6211.851/temp(K) + 14.009

 

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -6.826.

 

Run 3

Temperature

(°C)

Temperature

(K)

Reciprocal temperature

(K-1)

Mass difference

(μg)

Mass difference

(kg)

Vapour pressure

(Pa)

Log10Vp

130

403.15

0.002480466

14.29

1.429E-08

0.019838181

-1.702498150

131

404.15

0.002474329

14.81

1.481E-08

0.020560074

-1.686975320

132

405.15

0.002468222

18.04

1.804E-08

0.025044142

-1.601293846

133

406.15

0.002462145

18.80

1.880E-08

0.026099217

-1.583372529

134

407.15

0.002456097

19.86

1.986E-08

0.027570768

-1.559551135

135

408.15

0.002450080

21.71

2.171E-08

0.030139042

-1.520870555

136

409.15

0.002444091

22.82

2.282E-08

0.031680006

-1.499214739

137

410.15

0.002438132

24.61

2.461E-08

0.034164985

-1.466418765

138

411.15

0.002432202

26.94

2.694E-08

0.037399622

-1.427132787

139

412.15

0.002426301

30.92

3.092E-08

0.042924882

-1.367290893

140

413.15

0.002420428

33.00

3.300E-08

0.045812455

-1.339016439

141

414.15

0.002414584

35.01

3.501E-08

0.048602850

-1.31338268

142

415.15

0.002408768

39.44

3.944E-08

0.054752824

-1.261593472

143

416.15

0.002402980

42.00

4.200E-08

0.058306760

-1.234281088

144

417.15

0.002397219

48.57

4.857E-08

0.067427604

-1.171162275

145

418.15

0.002391486

55.95

5.595E-08

0.077672934

-1.109730288

146

419.15

0.002385781

65.67

6.567E-08

0.091166785

-1.040163362

147

420.15

0.002380102

74.70

7.470E-08

0.103702738

-0.984209777

148

421.15

0.002374451

79.78

7.978E-08

0.110755080

-0.955636347

149

422.15

0.002369926

91.18

9.118E-08

0.126581200

-0.897630791

150

423.15

0.002363228

99.48

9.827E-08

0.138103727

-0.859794602

A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 give the following statistical data using an unweighted least squares treatment.

 

Slope -7182.056

Standard deviation in slope 202.532

 

Intercept 16.074

Standard deviation in intercept 0.490

 

The results obtained indicate the following vapour pressure relationship.

Log10(Vp (Pa)) = 7182.056/temp(K) + 16.074

 

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -8.015.

 

Run 4

Temperature

(°C)

Temperature

(K)

Reciprocal temperature

(K-1)

Mass difference

(μg)

Mass difference

(kg)

Vapour pressure

(Pa)

Log10Vp

128

401.15

0.002492833

12.26

1.226E-08

0.017020021

-1.769039909

129

402.15

0.002486634

13.13

1.312E-08

0.018213921

-1.739596544

130

403.15

0.002480466

14.38

1.438E-08

0.019963124

-1.699771493

131

404.15

0.002474329

15.72

1.572E-08

0.021823387

-1.661077837

132

405.15

0.002468222

17.24

1.724E-08

0.023933537

-1.620993117

133

406.15

0.002462145

17.76

1.776E-08

0.024655430

-1.608087417

134

407.15

0.002456097

20.49

2.049E-08

0.028445370

-.1.545988420

135

408.15

0.002450080

21.03

2.103E-08

0.029195028

-1.534691106

136

409.15

0.002444091

23.13

2.312E-08

0.032096483

-1.493542549

137

410.15

0.002438132

24.83

2.483E-08

0.034470401

-1.462553659

138

411.15

0.002432202

25.72

2.572E-08

0.035705949

-1.447259414

139

412.15

0.002426301

28.59

2.859E-08

0.029690245

-1.401316223

140

413.15

0.002420428

28.95

2.894E-08

0.040190017

-1.395881811

141

414.15

0.002414584

32.32

3.232E-08

0.044868440

-1.348059027

142

415.15

0.002408768

33.50

3.350E-08

0.046506583

-1.332485572

143

416.15

0.002402980

38.25

3.825E-08

0.053100800

-1.274898939

144

417.15

0.002397219

40.75

4.075E-08

0.056571440

-1.247402766

145

418.15

0.002391486

43.50

4.350E-08

0.060389145

-1.219041122

146

419.15

0.002386781

45.59

4.559E-08

0.063290600

-1.198660787

147

420.15

0.002380102

49.82

4.983E-08

0.069176806

-1.160039492

148

421.15

0.002374451

53.37

5.337E-08

0.074091233

-1.130233176

A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.

 

Slope -5329.892

Standard deviation in slope 61.097

 

Intercept 11.524

Standard deviation in intercept 0.149

 

The results obtained indicate the following vapour pressure relationship.

Log10(Vp (Pa)) = -5329.892/temp(K) + 11.524

 

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -6.353.

 

Run 5

Temperature

(°C)

Temperature

(K)

Reciprocal temperature

(K-1)

Mass difference

(μg)

Mass difference

(kg)

Vapour pressure

(Pa)

Log10Vp

150

423.15

0.002363228

86.00

8.600E-08

0.119390033

-0.923031927

149

422.15

0.002368826

66.96

6.696E-08

0.092957635

-1.031714934

148

421.15

0.002374451

66.00

6.600E-08

0.091624909

-1.037986443

147

420.15

0.002380102

57.28

5.728E-08

0.079519315

-1.099527369

146

419.15

0.002385781

51.98

5.198E-08

0.072161557

-1.141694104

145

418.15

0.002391486

46.36

4.636E-08

0.064359557

-1.191386951

144

417.15

0.002397219

41.38

4.138E-08

0.057446041

-1.240739892

143

416.15

0.002402980

36.94

3.694E-08

0.051282184

-1.290033488

142

415.15

0.002408768

34.12

3.412E-08

0.047367301

-1.324521356

141

414.15

0.002414584

31.92

3.192E-08

0.044313138

-1.353467496

140

413.15

0.002420428

27.44

2.744E-08

0.038093750

-1.419146272

A plot Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 5 gives the following statistical data using an unweighted least squares treatment.

 

Slope -8114.666

Standard deviation in slope 291.807

 

Intercept 18.221

Standard deviation in intercept 0.698

 

The results obtained indicate the following vapour pressure relationship.

Log10(Vp (Pa)) = -8114.666/temp(K) + 18.221

 

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -8.996.

 

Summary of Results

Run

Log10 [Vp(25°C)]

1

-7.233

2

-6.826

3

-8.015

4

-6.353

5

-8.996

Mean                                    =             -7.485

Vapour Pressure  =             3.3 x 10-8 Pa

 

The test material did not change in appearance under the conditions used in the determination.

Conclusions:
The vapour pressure of APAN has been determined to be 3.3e-8 Pa at 25 °C.
Executive summary:

The test procedure was based on Method A4 specified in Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).

APAN has been determined to have a vapour pressure of 3.3 x 10-8Pa at 25 °C, using a vapour pressure balance.

Description of key information

APAN has been determined to have a vapour pressure of 3.3 x 10-8Pa at 25 °C, using a vapour pressure balance.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

The test procedure was based on Method A4 specified in Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).

APAN has been determined to have a vapour pressure of 3.3 x 10-8 Pa at 25 °C, using a vapour pressure balance.