Registration Dossier
Registration Dossier
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EC number: 251-238-9 | CAS number: 32817-15-5
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 431 (In Vitro Skin Corrosion: Reconstructed Human Epidermis (RHE) Test Method)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Copper glycinate
- EC Number:
- 251-238-9
- EC Name:
- Copper glycinate
- Cas Number:
- 32817-15-5
- Molecular formula:
- C2H5NO2.xCu
- IUPAC Name:
- copper glycinate
- Test material form:
- solid
Constituent 1
In vitro test system
- Test system:
- human skin model
Results and discussion
In vitro
Results
- Irritation / corrosion parameter:
- % tissue viability
- Value:
- 26
- Negative controls validity:
- valid
- Positive controls validity:
- valid
Applicant's summary and conclusion
- Interpretation of results:
- Category 1B (corrosive) based on GHS criteria
- Conclusions:
- In conclusion, in this in vitro skin corrosion test in EPISKIN model with COPPER GLYCINATE the results indicate that the test item is corrosive to skin after 4 hours and 1 hour of exposure time and not corrosive after 3 minutes of exposure time. According to the UN GHS classification systems, COPPER GLYCINATE has been categorized as “Corrosive: Optional Sub- categories 1B and 1C”.
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