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EC number: 230-468-3 | CAS number: 7149-10-2
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2001-02-08
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of method:
- flask method
Test material
- Reference substance name:
- 4-aminomethyl-2-methoxyphenol hydrochloride
- EC Number:
- 230-468-3
- EC Name:
- 4-aminomethyl-2-methoxyphenol hydrochloride
- Cas Number:
- 7149-10-2
- Molecular formula:
- C8H11NO2.ClH
- IUPAC Name:
- 4-aminomethyl-2-methoxyphenol hydrochloride
- Test material form:
- other: solid
- Details on test material:
- - Physical state: white solid
- Analytical purity: 99.77 %(w/w)
- Lot/batch No.: 77
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- 197 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 3
Any other information on results incl. tables
Table 1 Absorption, Concentration, pH
Sample description |
Age [h] |
Response |
Concentration found [mg/L] |
Dilution factor |
Concentration calculated [g/L] |
Measured pH |
Sample solution |
72 |
0.486 |
40.731 |
5000 |
204 |
3 |
Sample solution |
72 |
0.482 |
40.363 |
5000 |
202 |
3 |
Sample solution |
48 |
0.473 |
39.536 |
5000 |
198 |
3 |
Sample solution |
48 |
0.477 |
39.904 |
5000 |
200 |
3 |
Sample solution |
24 |
0.47 |
39.260 |
5000 |
196 |
3 |
Sample solution |
24 |
0.438 |
36.318 |
5000 |
182 |
3 |
Corresponding to the analysis the water solubility of the test item was calculated to be 197 g/L.
Applicant's summary and conclusion
- Conclusions:
- In conclusion, the water solubility of Vanillyamin-HCl was calculated to be 197 g/L at 20°C (mean value, 8 g/L standard deviation).
- Executive summary:
The test item has a water solubility of 197 g/L at 20°C as determined by flask method according to Regulation EC No. 440/2008 Method A.6 and OECD Test Guideline 105 (1995) and Product Properties test Guideline OPPTS 830.7840 of EPA (1996).
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