Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

The rate of hydrolysis of the substance was determined as t1/2 = <0.1 hours at pH 4, t1/2 = 8.7 hours at pH7 and t1/2 = 534 hours (22.3 days) at pH 9 in a read-across approach from a chemically related substance.

Thus in the case of the present substance, the diketo compound 18-methyl-5(10)-estren-3,17-dione should have been formed. This is consistent with the appearance of a HPLC peak with retention time ¿ 3.2 min in all hydrolyzed solutions which is increasing during hydrolysis.