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Diss Factsheets
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EC number: 204-469-4 | CAS number: 121-44-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Readily Biodegradability:
DECISION OF THE EU COMMISSION WORKING GROUP ON CLASSIFICATION AND LABELLING OF DANGEROUS SUBSTANCES:
this
group (= regulators from authorities of different European countries)
decided not to classify the substance due to ready biodegradability. See
below extract from minutes of two meetings of the group from 1995:
(1)
The
Commission Working Group on the Classification and Labelling of
dangerous substances agreed not to classify this substance as dangerous
to the environment due to ready biodegradability:
The
proposal was N; R51-53. CEFIC argued that the acute toxicity of this
substance was in the R52 range. Furthermore CEFIC reported
biodegradation tests indicating ready biodegradability within the 10 day
time window and there was no reference as to whether adapted
micro-organisms were used. CEFIC therefore proposed no classification.
DE noted that the acute toxicity for algae and a not ready test result
indicated N; R51-53. FR agreed with CEFIC that the substance needed no
classification due to the ready biodegradation. UK also agreed that a
ready test result in a biodegradation test should overrule a not ready
test result and therefore agreed with no classification.
Reference:
SUMMARY RECORD - Commission Working Group on the Classification and
Labelling of dangerous substances: Environmental Effects; ECBI/39/95 -
Rev. 1; 3-5 April 1995.
(2)
The
Commission Working Group on the Classification and Labelling of
dangerous substances confirmed the decision not to classify the
substance as dangerous for the environment.
Reference:
SUMMARY RECORD - Commission Working Group on the Classification and
Labelling of dangerous substances: Environmental Effects; ECBI/67/95 -
Rev. 1; 20-22 June 1995.
Conclusion:
The chemical should be regarded as readily biodegradable based on the
decision of European regulators.
Discussion of available data:
Several studies are available, but these results can only be assigned as additional, supporting information: In former times (1977) BASF AG performed already an experimental study in the context of ready biodegradability for 10 days following no guideline, but using a scientifically acceptable method. The inoculum was industrial, adapted, activated sludge and TEA was stated to be biodegradable in water.
A study report for ready biodegradability published 2001 at Elf Atochem Inc. stated that the test substance is readily biodegradable due to the fact that 96 % degradation has occurred during a study period of 21 days. It is not indicated which inoculum or test system was used, just that it was done under aerobic conditions.
The Japan Chemical Industry testing laboratory investigated the inherent biodegradability of TEA in 1992 according to OECD guideline 302 C. The inoculum was non-adapted activated sludge and an initial test material concentration of 30 mg/L was used. The test duration was 28 days under aerobic conditions. A degradation of 25 – 34 % was reported as test result in this case.
Conclusion: Based on the results of the available studies, the test substance is readily biodegradable.
To fulfill the intention of read-across, the following data are available:
BASF AG (1990) performed a screening test for biodegradation in water for the chemical similar substance tripropylamine. This was a ready biodegradability test according to OECD guideline 301 E. The inoculum was domestic, non-adapted activated sludge under aerobic conditions. The duration of the test was 28 days, with an initial concentration of 28 mg/L, based on test material (TEA). Due to the fact that only 0 – 10 % degradation was investigated the scientists stated that no biodegradation was observed under these conditions.
Another read-across was done to the chemical similar substance tributylamine (Muckle, 2010). The substance was tested for ready biodegradability according to OECD guideline 301 B. Activated sludge from a waste water treatment plant receiving mostly domestic sewage was used as inoculum. The test concentration was 20 mg/L organic carbon (nominal). Degradation in the two replicates at the end of the 10 -day window reached 43 % and 71 %, respectively. Due to a deviation during the degradation phase within replicates, degradation lay marginally below the pass level (57 % instead of 60 %). This might be due to dissolved carbon dioxide in the test flasks. At the end of the test this dissolved carbon dioxide is driven off by addition of HCl, leading to an improved correlation between the replicates. At the end of the test, the difference between the replicates was only 6.4 %. The mean degradation at the end of the test was 80 %. Therefore, form a scientific point of view, the tributylamine is considered as readily biodegradable according to OECD criteria.
According to REACH regulation, no further testing of biodegradation characteristics (water and sediment or soil) have to be conducted due to the fact that the substance triethylamine is considered as readily biodegradable regarding the decision of the EU Commission Working Group on Classification and Labelling of Dangerous Substances.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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