Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 937-960-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 Apr 2016 to 16 Apr 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Swiss Federal Office for the Environment (FOEN)
- Type of method:
- flask method
- Key result
- Water solubility:
- 2 667 mg/L
- Temp.:
- 20 °C
- pH:
- 2.9
- Conclusions:
- During this study, the water solubility of the test item was determined at 20°C at a mean pH value of 2.9 using the shake flask method according to OECD 105. The water solubility was found to be 2667 mg/L. Due to the reasons given earlier, the value has to be seen as an approximation.
Reference
Results
The tabulated values (see Tables 1 and 2) represent results based on evaluation of sum of peak areas of two main peaks.
Table 1: Results of the Water Solubility of the test item - Higher loading rating (about 12.5 g/L)
Sample No. |
Shaking time at 30°C [hours] |
Measured concentration* [mg/L] |
Water Solubility Mean Value [mg/L] |
Overall Mean ± Std. Dev. [mg/L] |
Rel. Std. Dev. [%] |
72 -3 72 -4 |
72 72 |
2275 2300 |
2288 |
2480 +/- 190 |
+/- 7.7 % |
48 -3 48 -4 |
48 48 |
2499 2473 |
2486 |
||
24 -3 24 -4 |
24 24 |
2664 2670 |
2667 |
* measured concentration represents mean value of duplicate measurements of the samples with different dilution factors
Table 2: Results of the Water Solubility of the test item - Lower loading rating (about 1.3 to 1.7 g/L)
Sample No. |
Shaking time at 30°C [hours] |
Measured concentration* [mg/L] |
Water Solubility Mean Value [mg/L] |
Overall Mean ± Std. Dev. [mg/L] |
Rel. Std. Dev. [%] |
72 -1 72 -2 |
72 72 |
869 963 |
916 |
1044 +/- 177 |
+/- 11.2 % |
48 -1 48 -2 |
48 48 |
1117 1028 |
1073 |
||
24 -1 24 -2 |
24 24 |
1157 1132 |
1145 |
* measured concentration represents mean value of duplicate measurements of the samples with different dilution factors
At the higher loading rate (about 12.5 g/L) an overall mean content in water of 2480 ± 190 mg/L was obtained. At the lower loading rate (about 1.3 to 1.7 g/L) an overall mean of 1044 ± 117 mg/L was obtained. The different values can be due to the composition of the test item consisting of four constituents with different water solubilities. Obviously at the lower loading rate, the saturation of the water with the more soluble compounds was not yet achieved, although the test item appeared as insoluble. Furthermore, the test item shows some instability during the performance of the test: a peak near the column dead time increased with increasing shaking time and also as compared to the content of this peak in the calibration solutions, while the two main peaks taken for evaluation decreased with increased shaking time.
Due to the instability of the test item and the incomplete saturation of water with some compounds at the lower loading rate, the water solubility was derived from the values obtained after 24 hours shaking time, performed with the assay at the higher loading rate. The water solubility of the test item - based on evaluation of two main peaks representing several compounds of the test item - was found to be 2667 mg/L.
It should be pointed out that the given value is an approximated value, since the test item consists of four constituents with different solubilities, affecting each other. Although the guideline OECD 105 is applicable from a technical point of view, the scientifical validity of water solubility determinations is restricted to essentially pure compounds.
Description of key information
Water solubility: 2667 mg/L at 20 °C, pH = 2.9 (OECD 105)
Key value for chemical safety assessment
- Water solubility:
- 2 667 mg/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of the test item was determined at 20°C at a mean pH value of 2.9 using the shake flask method according to OECD 105. The water solubility was found to be 2667 mg/L. Since the test item is a mixture of four constituents with different solubilities, the value should be regarded as an approximated value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.