Decene, hydroformylation products, low boiling

Long-term toxicity to aquatic invertebrates

Description of key information

The long-term toxicity to invertebrates of components of Alchisor TAL 111 has been documented within this dossier. Adequate reliable measured data exists for long-term toxicity to invertebrates to components of Alchisor TAL 111 (namely, C9 -C14 aliphatics (2 -25% aromatics)).  The study by Exxon (2005) reports a NOEC for long-term toxicity to aquatic invertebrates of 0.097 mg/l or NOELR of 0.28 mg/l. Consequently the NOEL value will be taken as the long-term toxicity to aquatic invertebrate’s endpoint for Alchisor TAL 111 as it is camparable with the NOEL for long-term toxicity to fish and algae.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

0.28 mg/L

Additional information

Alchisor TAL 111 is decene, hydroformylation product, low boiling and can be characterised as a UVCB substance. As defined in the ‘Read-Across Justification Document’ section 13, data provided for the analogue substance Alchisor TAL 123 and the Alchisor TAL 111 consitutent category substances, Category 3 hydrocarbon solvents, are representative of Alchisor TAL 111 and suitable for assessment purposes. Study data for each analogue/constituent category has been evaluated and considered together. One reliable (Klimisch 1) long-term toxicity study in invertebrates has been conducted for constituent categoriesof Alchisor TAL 111 (namely, C9 -C14 aliphatics (2 -25% aromatics)), although no studies are available for the analogue substance Alchisor TAL 123, and are included in this dossier.In a conservative approach the most sensitive study result from across the constituent categories will be identified and used to address the hazard endpoint in question.

C9-C14 Aliphatics (2-25% Aromatics)

One reliable (Klimisch 1) long-term toxicity study result for invertebrates was available forC9-C14 aliphatics (2-25% aromatics). The study was provided by Exxon Biomedical Sciences, Inc (2005), was a GLP compliant OECD 211 study with Hydrocarbons (C9 -C14 aliphatics (2 -25% aromatics)) and Daphnia magna were exposed for 21 days to nominal loading concentrations of the test chemical. The EL10 based on reproduction was 0.316 mg/l. The EC10 based on reproduction was 0.109 mg/l. Reproduction was more sensitive than growth and survival, resulting in a NOELR of 0.28 mg/l and a NOEC of 0.097 mg/l.

 

The long-term toxicity to invertebrates of constituent categoriesof Alchisor TAL 111 has been documented within this dossier. Adequate reliable measured data exists for long-term toxicity to invertebrates to constituent categoriesof Alchisor TAL 111 (namely, C9 -C14 aliphatics (2 -25% aromatics)). The most sensitive and reliable endpoint is a NOEC for long-term toxicity to aquatic invertebrates of 0.097 mg/l and a NOELR of 0.28 mg/l. The NOELR is considered to be directly comparable with NOELR reported for fish and algae and consequently this value will be taken as the long-term toxicity to aquatic invertebrate’s endpoint for Alchisor TAL 111.