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Diss Factsheets

Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 February 2013
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Conducted in accordance with ASTM D5191 − 12 Standard Test Method for Vapor Pressure of Petroleum Products (Mini Method). This is a non-GLP method, and is considered to be a K2 study, on the basis that it is an accepted method and describes the vapour pressure derivation for oil based products accurately.
Qualifier:
according to guideline
Guideline:
other: ASTM D5191 − 12 Standard Test Method for Vapor Pressure of Petroleum Products (Mini Method)
Deviations:
not applicable
Principles of method if other than guideline:
This test method covers the use of automated vapor pressure instruments to determine the total vapor pressure exerted in vacuum by air-containing, volatile, liquid petroleum products, including automotive spark-ignition fuels with or without oxygenates (see Note 1). This test method is suitable for testing samples with boiling points above 0°C (32°F) that exert a vapor pressure between 7 and 130 kPa (1.0 and 18.6 psi) at 37.8°C (100°F) at a vapor-to-liquid ratio of 4:1.Measurements are made on liquid sample sizes in the range from 1 to 10 mL. No account is made for dissolved water in the sample.
GLP compliance:
no
Type of method:
effusion method: by loss of weight or by trapping vaporisate
Temp.:
37.8 °C
Vapour pressure:
1.22 kPa
Remarks on result:
other: Dry vapour pressure.
Conclusions:
The substance demonstrated a dry vapour pressure of 1.22 kPa at 37.8 deg C. This is considered appropriate for hazard assessment purposes, and demonstrates that the substance does not have a high vapour pressure.
Executive summary:

The substance demonstrated a dry vapour pressure of 1.22 kPa at 37.8 deg C. This is considered appropriate for hazard assessment purposes, and demonstrates that the substance does not have a high vapour pressure.

Description of key information

Vapour pressure.

Key value for chemical safety assessment

Vapour pressure:
1.22 kPa
at the temperature of:
37.8 °C

Additional information

The substance demonstrated a dry vapour pressure of 1.22 kPa at 37.8 deg C. This is considered appropriate for hazard assessment purposes, and demonstrates that the substance does not have a high vapour pressure. The study was conducted in accordance with ASTM D5191 − 12 Standard Test Method for Vapor Pressure of Petroleum Products (Mini Method). This is a non-GLP method, but is considered to be a K2 study, on the basis that it is an accepted method and describes the vapour pressure derivation for oil based products accurately.

The Klimish rating is considered appropriate in accordance with ANNEX XI-GENERAL RULES FOR ADAPTATION OF THE STANDARD TESTING REGIME SET OUT IN ANNEXES VII TO X, Para 1.1.1 which states that:

 

1.1.1. Data on physical-chemical properties from experiments not carried out according to GLP or the test methods referred to in Article 13(3)

 

Data shall be considered to be equivalent to data generated by the corresponding test

methods referred to in Article 13(3) if the following conditions are met:

1) adequacy for the purpose of classification and labelling and/or risk assessment;

2) sufficient documentation is provided to assess the adequacy of the study; and

3) the data are valid for the endpoint being investigated and the study is performed using an acceptable level of quality assurance.

The data presented is considered to fulfil the above, as it is conducted in accordance with recognised non-GLP methods, suitable for the determination of the endpoint specific to the product type, but a suitable qualified external laboratory services provider.