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Diss Factsheets
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EC number: 202-860-4 | CAS number: 100-52-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
Two relevant studies on the impairment of fertility caused by benzaldehyde are mentioned in the German MAK report on benzaldehyde (1998).
10 female rats were given oral doses of 2 mg benzaldehyde per animal (about 5 mg!kg body weight and day) every second day for a period of 223 days, and were mated with untreated males on days 75 and 108 after the beginning of treatrnent. The control group consisted of 10 untreated females. The number of offspring. the weight of the pups after 1 and 3 weeks and survival of the pups was in the range of the control values. The number of pregnant females in the lest group was decreased relative to that in the control group (Sporn et al. 1967). The study design (small number of treated animals, only one dose group) does not meet present-day standards and cannot, therefore, be regarded as evidence of impairrnent of female fertility. In a medium-terrn study with male F344 rats (for more details see Section 5.2.2) decreased testis weights were observed, but the effective dose of 800 mg/kg body weight (dissolved in corn oil, administered by gavage) was highly toxic and led to the death of 6 of 10 animals, so that this finding cannot be regarded as evidence of an impairment in fertility. In the 400 mg/kg group, in which there were no deaths or signs of intoxication, this effect did not occur (Kiuwe et al. 1983, NTP 1990).
Effects on developmental toxicity
Additional information
There are no developmental toxicity studies available.
Justification for classification or non-classification
The above presented data on impairement of fertility, are not sufficient and conclusive for classification.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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