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Diss Factsheets
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EC number: 611-084-9 | CAS number: 54041-17-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- - Type: aquatic mixed population of microorganisms (activated sludge)
- Origin: secondary effluent of a domestic sewage treatment plant (Wupper area water authority)
- sampling date: 18.02.1994
- Pre-Treatment: None - Duration of test (contact time):
- 28 d
- Initial conc.:
- 4.2 mg/L
- Based on:
- test mat.
- Details on study design:
- A measured volume of mineral medium containing a known concentration of the test substance and inoculum was incubated under aerobic conditions in the dark for 28 d at 20 - 21 °C. The endogenous activity of the inoculum was checked by running parallel blanks with inoculum but without test item. A reference compound (Aniline) was run in parallel to check the operation of the procedures. A toxicity control was run in duplicate.
Degradation was followed by the determination of oxygen uptake and measurements were taken at frequent intervals to allow the identification of the beginning and end of biodegradation. - Reference substance:
- aniline
- Remarks:
- purity: 99.5 %
- Parameter:
- % degradation (O2 consumption)
- Value:
- 2
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 3
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 21 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 4
- Sampling time:
- 28 d
- Details on results:
- The calculation of degradation was done under the presumption of no nitrogen oxidation.
- Results with reference substance:
- After 14 d more than 80 % of the reference substance aniline were degraded.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- A biodegradation of 4% was determined for the test substance after 28 d.
- Executive summary:
A study was conducted in accordance with the Council Regulation (EC) Method C.4-E “Closed Bottle Test“.The test item was dissolved in a mineral medium, which was inoculated with a mixed population of aquatic microorganisms and incubated under aerobic conditions in the dark at 20 - 21 °C for 28 days.The endogenous activity of the inoculum was checked by running parallel blanks with inoculum but without test item. A reference compound (Aniline) was run in parallel to check the operation of the procedures. A toxicity control was run in duplicate.
Degradation was followed by the determination of oxygen uptake and measurements were taken at frequent intervals to allow the identification of the beginning and end of biodegradation. A biodegradation of 4% was determined for the test substance after 28 d.
Reference
Description of key information
A study was conducted in accordance with the Council Regulation (EC) Method C.4-E “Closed Bottle Test“.The test item was dissolved in a mineral medium, which was inoculated with a mixed population of aquatic microorganisms and incubated under aerobic conditions in the dark at 20 - 21 °C for 28 days.The endogenous activity of the inoculum was checked by running parallel blanks with inoculum but without test item. A reference compound (Aniline) was run in parallel to check the operation of the procedures. A toxicity control was run in duplicate.
Degradation was followed by the determination of oxygen uptake and measurements were taken at frequent intervals to allow the identification of the beginning and end of biodegradation. A biodegradation of 4% was determined for the test substance after 28 d.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.