Registration Dossier
Registration Dossier
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EC number: 203-756-1 | CAS number: 110-31-6
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (21 d) ≥ 0.0056 mg/L for Daphnia magna (OECD 211, limit test). No toxicity in the range of solubility.
Key value for chemical safety assessment
Additional information
There is no data available on the toxicity to invertebrates potential of Amides, C16 and C18-C20 (even numbered, unsaturated), N,N’-ethylenebis. In order to fulfil the standard information requirements set out in Annex IX, 9.1.5, in accordance with Annex XI, 1.5, of Regulation (EC) No 1907/2006, read-across from a structurally related substance is conducted. A detailed justification for the grouping of chemicals and read-across is provided in the technical dossier (see IUCLID Sections 6.1 and 13). The long-term toxicity of Amides, C16 and C18-C20 (even numbered, unsaturated), N,N’-ethylenebis to aquatic invertebrates was assessed in a read across approach using the structural analogue Amides, C16-C18 (even), N,N'-ethylenebis. The long-toxicity of the test item to Daphnia magna was investigated in one key study from the Japanese Ministry of Environment (MOE, 2005). This semi-static study was conducted according to OECD 211. Daphnids were exposed to a limit concentration of nominal 100 mg/L (corresponding to 0.00564 mg/L measured concentration). After 21 d of exposure to the test substance no effects on reproduction were reported up to the highest attainable concentration (0.0056 mg/L, limit of solubility). Therefore, the EC50 and NOEC (21 d) were > 0.0056 mg/L, and no toxicity within the range of water solubility was observed.
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