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Diss Factsheets
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EC number: 208-645-1 | CAS number: 536-74-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- not specified
- Remarks:
- Data on Vapour Pressure comes from Safety Data Sheet.
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Data on Vapour Pressure comes from the Safety Data Sheet.
- Justification for type of information:
- Data on Vapour Pressure comes from Safety Data Sheet. This is not considered critical for the assessment. Therefore validation applies with acceptable restrictions.
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: Data on Vapour Pressure comes from Safety Data Sheet. No information on TEST GUIDELINE provided.
- GLP compliance:
- not specified
- Type of method:
- other: Data on Vapour Pressure comes from Safety Data Sheet. No information on TYPE OF METHOD provided.
- Key result
- Temp.:
- ca. 37.7 °C
- Vapour pressure:
- ca. 23.465 hPa
- Remarks on result:
- other: Data as reported into the Safety Data Sheet
- Conclusions:
- Vapour Pressure of test item is stated to be 23.4647 hPa at 37.7 °C .
- Executive summary:
The Vapour Pressure of test item comes from the Safety Data Sheet of manufacture
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- December 2021
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- QSAR prediction:
The value is not an experimental result, however the QSAR model is recommended by the ECHA guidance document on information requirements, and is well documented with regard to validation parameters according to OECD principles. In addition, the substance investigated matches with the parameters of training set compounds and the result is considered as reliable with restriction. - Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- QSAR Estimation
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 275 Pa
- Remarks on result:
- other: PATTE,F et AL. (1982)
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 773 Pa
- Remarks on result:
- other: Mean of Antoine & Grain methods (5.8 mmHg)
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 836 Pa
- Remarks on result:
- other: Antoine Method (6.27 mmHg)
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 710 Pa
- Remarks on result:
- other: Modified Grain Method (5.33 mmHg)
- Conclusions:
- The Vapour Pressure for the test substance is estimated to be ca 773 Pa (average value) at 25°C, using a boiling point of 142°C as input.
- Executive summary:
Vapour pressure of the test substance was estimated with the QSAR model MPBPWIN from Episuite.
Referenceopen allclose all
Description of key information
Vapour Pressure of test item is stated to be 23.4647 hPa at 37.7 °C .
Key value for chemical safety assessment
- Vapour pressure:
- 23.465 hPa
Additional information
A reliable Vapour Pressure data of test item was available on the Safety Data Sheet of manufacturer. Some restrictions apply so a QSAR estimation was performed to confirm this value.
The Vapour Pressure was estimated by QSAR (EpiSuite) using the boiling point as input.
The calculated (QSAR) Vapour Pressure confirmed the Vapour Pressure by the manufacturer of substance. This is retained as key result.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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